Sökning: "endocrine tumour"

Visar resultat 16 - 20 av 36 avhandlingar innehållade orden endocrine tumour.

  1. 16. Pheochromocytoma and abdominal paraganglioma : clinical and genetic aspects

    Författare :Elisabet Edström Elder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pheochromocytomas; abdominal paragangliomas; RET; MEN 2A; tumour development; chromosome 1; comparative genomic hybridisation; in situ hybridization; loss of heterozygosity.;

    Sammanfattning : Pheochromocytomas and abdominal paragangliomas are rare catecholamine producing tumours arising from sympathoadrenal paraganglia located within and outside of the adrenal medulla, respectively. The great majority of tumours are benign and cured by surgery. LÄS MER

  3. 17. Genetic background of familial primary hyperparathyroidism

    Författare :Andrea Villablanca; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Parathyroid; primary hyperparathyroidism; MEN 1; HPT-JT; FIHP; Menin; Parafibromin; tumour suppressor gene; loss of heterozygosity; mutation analysis; immunohistochemistry;

    Sammanfattning : In this thesis the aim has been to identify and characterise gene(s) involved in familial primary hyperparathyroidism (PHPT). In multiple endocrine neoplasia type 1 (MEN 1), the hyperparathyroidism-jaw tumour syndrome (HPT-JT) and familial isolated hyperparathyroidism (FIHP), in which primary hyperparathyroidism is seen in most or almost all gene carriers. LÄS MER

  4. 18. Ovarian tumours, cell isolation, cell survival and sex steroids

    Författare :Magdalena Taube; Seija Grénman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Obstetrik och gynekologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Background: Ovarian cancer is the most deadly malignancy of the female reproductive tract. Ovarian epithelial tumours are considered to be endocrine related, but the factors that govern their genesis and progression remain unclear. Radical surgery and recent advances in chemotherapy have only moderately improved survival rates. LÄS MER

  5. 19. Vesicle proteins as markers for neuroendocrine tumors

    Författare :Anne-Marie Levin Jakobsen; Göteborgs universitet; []
    Nyckelord :Neuroendocrine tumours; gastrointestinal tract; pancreas; adrenal; vesicle proteins; ; SV2; NESP55; VMAT1; VMAT2; MIBG;

    Sammanfattning : The neuroendocrine (NE) tumours comprise a diversity of tumours which share commonproperties, e.g. the capacity to produce, store and release hormones. A prominent feature ofthe NE phenotype is the production of secretory granules with associated vescicle proteins,e. LÄS MER

  7. 20. Phosphorylation of ERα and HIF-1α in breast cancer with focus on tamoxifen response and links to kinase activation

    Författare :Caroline Wigerup; Malmö Patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Anti-oestrogens are commonly used in adjuvant breast cancer treatment and for a long time tamoxifen has been the main endocrine treatment. Patients who are eligibly for endocrine treatment are selected by the tumour-specific expression of oestrogen receptor (ER) and approximately 70 % of all breast cancer patients are classified as ER positive. LÄS MER