Sökning: "MEN 2A"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden MEN 2A.

1. 1. Hypoxia-induced phenotypic modulation of human neuroblastoma cells

   Författare :Linda Holmquist Mengelbier; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; reoxygenation; HIF-2a; HIF-1a; differentiation; hypoxia; neuroblastoma;

   Sammanfattning : Neuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. LÄS MER

3. 2. Beta cell function in autoimmune diabetes in young adults

   Författare :Carina Törn; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ketoacidosis; insulin treatment; prognostic factors; C-peptide; type 2; type 1; IA-2A; ICA; GADA; IAA; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : This thesis presents the results from a study of the first four years of diabetes in 879 patients aged 15-34 years at diagnosis. The aims of this study were to compare clinical classification with the presence of autoantibodies, to study the natural course of beta cell function during the first years of disease and to define predictive factors for the remaining beta cell function after diagnosis. LÄS MER

4. 3. Epidemiology of diabetes in a well defined population in Sweden: the Skaraborg Diabetes Registry

   Författare :Bo Berger; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; diabetologi; Endokrinologi; diabetology; secreting systems; Endocrinology; Medicin människa och djur ; Medicine human and vertebrates ; IA-2A; GADA; ICA; islet antibodies; C-peptide; mortality; prevalence; serology; transplantation; Immunologi; serologi; Public health; incidence; epidemiology; epidemiologi; sekretion; Folkhälsa;

   Sammanfattning : Time trends in prevalence, incidence and mortality was followed in 15000 diabetic patients in 1991?2005. Clinical findings, C-peptide protocols, and islet antibodies were compared in their ability to distinguish type 1 from type 2 diabetes, and factors associated with the prognosis of diabetes were explored. LÄS MER

5. 4. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

   Författare :Henrik Borg; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; secreting systems; Endocrinology; seropositive; seronegative; slowly-progressive; Type 2; Type 1; classification; IA-2A; IA-2; GADA; GAD; ICA; islet antibodies; C-peptide; beta cell function; diabetes mellitus; adult-onset; sekretion; diabetologi;

   Sammanfattning : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. LÄS MER

7. 5. Modeling of Magnetic Fields and Extended Objects for Localization Applications

   Författare :Niklas Wahlström; Fredrik Gustafsson; Thomas B. Schön; Simon Maskell; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Localization; magnetic tracking; extended target tracking; signal processing; machine learning; Gaussian processes; deep dynamical model; discretization;

   Sammanfattning : The level of automation in our society is ever increasing. Technologies like self-driving cars, virtual reality, and fully autonomous robots, which all were unimaginable a few decades ago, are realizable today, and will become standard consumer products in the future. LÄS MER