Sökning: "enaminone"

Hittade 2 avhandlingar innehållade ordet enaminone.

  1. 1. Antiadhesive agents targeting uropathogenic Escherichia coli : Multivariate studies of protein-protein and protein-carbohydrate interactions

    Författare :Andreas Larsson; Jan Kihlberg; Fredrik Almqvist; Mats Larhed; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Antibacterial; pili; antiadhesive agents; structure based design; statistical molecular design; 2-pyridone; amino acid derivative; galabiose; enaminone; SPR; ELISA; QSAR; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes studies directed towards development of novel antiadhesive agents, with particular emphasis on compounds that prevent attachment of bacteria to a host-cell. Three different proteins involved in the assembly or function of adhesive pili in uropathogenic Escherichia coli have been targeted either by rational structure based design or statistical molecular methods. LÄS MER

  2. 2. An Environmental Approach to PVC Stabilisation

    Författare :Paul Clucas; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; organic stabiliser; base catalysed dehydrochlorination; colour improvement ; dehydrochlorination stability; polymer-bound stabiliser; intrasequence lactonisation; co-stabiliser; PVC stabilisation; colour stability; labile chlorine substitution; neighbouring group participation;

    Sammanfattning : We were interested in investigating the stabilisation behaviour of 6-aminouracils, a new class of heavy metal free thermo-stabiliser for PVC. We have therefore investigated the performance and mechanism of stabilisation for 1,3-dibutyl-6-aminouracil, both alone, and in combination with a sodium perchlorate co-stabiliser. LÄS MER