Sökning: "early-onset"

Visar resultat 6 - 10 av 193 avhandlingar innehållade ordet early-onset.

  1. 6. Biochemical and Epidemiological Studies of Early-Onset and Late-Onset Pre-Eclampsia

    Författare :Anna-Karin Wikström; Matts Olovsson; Ulf Eriksson; Solveig Norden-Lindeberg; Göran Berg; Uppsala universitet; []
    Nyckelord :Obstetrics and gynaecology; pre-eclampsia; proteinuria; albumin-creatinine ratio; ischaemic heart disease; angiogenesis; sFlt1; oxidative stress; isoprostane; PAI-1; PAI-2; Obstetrik och kvinnosjukdomar;

    Sammanfattning : Biochemical and epidemiological aspects of pre-eclampsia were investigated, with the main focus on possible pathophysiological differences between early-onset and late-onset disease.In pre-eclamptic women poor correlation was found between albumin-creatinine ratio (ACR) in a random urine sample and total amount of albumin in a 24-hour urine collection. LÄS MER

  3. 7. Life-course characteristics associated with early onset of sexual intercourse in females : in a context of relationships, self-perception, well-being and adjustment

    Författare :Chris Magnusson; Mona Eliasson; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Teenage girls; Self-perception; Kvinnlig sexualitet; psykologiska aspekter; Tonårsflickor; Självuppfattning; psykologi; Psychology;

    Sammanfattning : The dissertation treats early onset of sexual intercourse among adolescent females from a broad life-course perspective. Its main focus is on the structures and processes involved in the early onset of sexual intercourse in the contexts of personal relationships, well-being, self-perception and adjustment.Data are based on four cohorts of females. LÄS MER

  4. 8. Genotypic and phenotypic spectrum of mitochondrial diseases with focus on early onset mitochondrial encephalopathies

    Författare :Kalliopi Sofou; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitochondrial diseases; mitochondrial encephalopathy; Alpers syndrome; Leigh syndrome; neuroimaging; whole exome sequencing;

    Sammanfattning : Early-onset mitochondrial encephalopathies comprise a challenging group of neurodegenerative disorders. This is due to their progressive nature, often leading to major disability and premature death, as well as their diagnostic complexity and lack of customized treatments. LÄS MER

  5. 9. Early onset spine deformity : outcome of surgical treatment and 3D movement analysis of sitting

    Författare :Girts Murans; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Early onset, non-idiopathic spine deformities are progressive and associated with increased respiratory and cardiovascular morbidity and mortality as well as neurological and functional deteriorations. If untreated, the deformity progression can continue throughout the adult life and conclude with early mortality mostly due to cardio-pulmonary reason. LÄS MER

  7. 10. A multi-tracer PET approach to study early-onset familial and sporadic Alzheimer's disease

    Författare :Michael Schöll; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cumulated scientific evidence suggests that the pathology causing Alzheimer's disease (AD) occurs many years or even decades before memory impairment and other clinical symptoms arise. Tangible and detailed knowledge about different pathological processes, their interactions, and time course is therefore of the essence both for the development of potentially successful treatments and a reliable early diagnosis of this relentless disorder. LÄS MER