Sökning: "desmin"

Visar resultat 16 - 19 av 19 avhandlingar innehållade ordet desmin.

  1. 16. Role of Caveolae and miRNAs in Regulation of Urinary Bladder Function

    Författare :Mardjaneh Karbalaei; Cellulär biomekanik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The urinary bladder is responsible for storage and expulsion of urine. Proper urination depends on an ability of the bladder to adjust to increasing volume and to contract during micturition. A disturbance of bladder contractility may affect continence. LÄS MER

  3. 17. Studies in sporadic inclusion body myositis

    Författare :Snjólaug Arnardóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord : s-IBM; muscle fibre regeneration; cytoskeleton; IVIg; muscle inflammtion; cytokine; training; sensibility; neuropathy ;

    Sammanfattning : Aims: The general aims of the present study were to increase the understanding of the disease process in s-lBM by analysing the cytoskeletal structure in muscle fibres and their regeneration potential; and also to evaluate sensory function in patients with s-IBM to test the hypothesis of an associated neurogenic component or a concomitant neuropathy in s-IBM; and to evaluate therapeutic options by analysing the effect of IVIg treatment on the muscle inflammation; and to evaluate the effect of training on muscle function and muscle inflammation. Patients: Twenty-six patients with the diagnosis of s41BM participated in these studies. LÄS MER

  4. 18. Genetic studies of zebrafish muscles : clues to protection in muscle disease

    Författare :Nils Dennhag; Fatima Pedrosa Domellöf; Jonas von Hofsten; Tatjana Haitina; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; zebrafish; muscle; extraocular muscles; intermediate filaments; bioinformatics; genetics; CRISPR Cas9; oftalmiatrik; ophthalmology; cellforskning; cell research;

    Sammanfattning : Muscular dystrophies (MDs) are caused by dysregulation of over 40 proteins but commonly share features of muscle weakness, myofiber death and regeneration, loss of ambulation and premature death. A MD involves a broken link anywhere in the connection from extracellular matrix through the sarcolemma to the sarcomere. LÄS MER

  5. 19. Isolation and characterization of adult neural stem cells

    Författare :Clas B Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Intermediate filaments; GFAP; nestin; scar formation; regeneration; rodent and human neural stem cells; multipotency.;

    Sammanfattning : Injury to the central nervous system (CNS) is one of man's most handicapping situations resulting in severe functional impairment and in some cases a vegetative state where life is supported artificially. The brain and spinal cord, constituting the CNS, have been viewed for decades as having limited capacity of regeneration with no neurogenesis in the adult. LÄS MER