Sökning: "s-IBM"

Hittade 2 avhandlingar innehållade ordet s-IBM.

1. 1. Studies in sporadic inclusion body myositis

   Författare :Snjólaug Arnardóttir; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord : s-IBM; muscle fibre regeneration; cytoskeleton; IVIg; muscle inflammtion; cytokine; training; sensibility; neuropathy ;

   Sammanfattning : Aims: The general aims of the present study were to increase the understanding of the disease process in s-lBM by analysing the cytoskeletal structure in muscle fibres and their regeneration potential; and also to evaluate sensory function in patients with s-IBM to test the hypothesis of an associated neurogenic component or a concomitant neuropathy in s-IBM; and to evaluate therapeutic options by analysing the effect of IVIg treatment on the muscle inflammation; and to evaluate the effect of training on muscle function and muscle inflammation. Patients: Twenty-six patients with the diagnosis of s41BM participated in these studies. LÄS MER

3. 2. Myosin myopathy. A new disease entity

   Författare :Homa Tajsharghi; Göteborgs universitet; []
   Nyckelord :Neuromuscular disorders; Myosin myopathy; Myosin heavy chain; Myosin storage myopathy;

   Sammanfattning : By the discovery and characterization of two familial myopathies caused by mutations in myosin heavy chaingenes, we introduce a new entity within the field of neuromuscular disorders: Myosin myopathyThe first myopathy affected a family in western Sweden. Previous linkage analysis had located the gene tochromosome 17p13. LÄS MER