Sökning: "nestin"

Visar resultat 1 - 5 av 31 avhandlingar innehållade ordet nestin.

  1. 1. The muscle cytoskeleton of mice and men : Structural remodelling in desmin myopathies

    Författare :Lena Carlsson; Lars-Eric Thornell; Anders Arnér; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; desmin; nestin; synemin; paranemin; plectin; αB-crystallin; skeletal muscle; heart muscle; myotendinous junction; motor endplate; costamere; anatomi; Human Anatomy;

    Sammanfattning : The muscle fibre cytoskeleton of skeletal and heart muscle cells is composed mainly of intermediate filaments (IFs), that surround the myofibrils and connect the peripheral myofibrils with the sarcolemma and the nuclear membrane. Desmin is the first muscle specific IF protein to be produced in developing muscles and is the main IF protein in mature muscles. LÄS MER

  3. 2. Nestin : filament formation and expression in myogenesis and muscle disorders

    Författare :Gunnar Sjöberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Intermediate filament; nestin; desmin; vimentin; myogenesis neuromusculardisorders; rhabdomyosarcoma;

    Sammanfattning : Intermediate filaments (IF), together with microfilaments and microtubules, are the major components of the cytoskeleton of eukaryotic cells. In myogenic cells three IF proteins are expressed; desmin, vimentin and nestin. LÄS MER

  4. 3. Nestin regulation in the embryonic and adult CNS

    Författare :Carina Lothian; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The developing mammalian central nervous system (CNS), i.e. the brain and spinal cord, is generated from neuroectodermal stem/progenitor cells lining the neural tube. The CNS stem/progenitor cells proliferate and migrate to give rise to the three principal cell types in the developing CNS: neurons, astrocytes and oligodendrocytes. LÄS MER

  5. 4. A study of the cell adhesions molecules, E-cadherin and C-CAM, and the intermediate filaments, nestin, in craniofacial and tooth development

    Författare :Catharina Terling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cell adhesion molecules; epithelial fusion; C-CAM; E-cadherin; junctional epithelium; nestin; odontogenesis; palate;

    Sammanfattning : Cell adhesion molecules (CAMs) are involved in cell migration, morphogenesis, and cell differentiation within the embryo, and later in the maintenance of the multicellular organism. The aim of the present investigation was to analyze and compare the distribution of the CAMs, E-cadherin and C-CAM, during odontogenesis and palate formation, and furthermore, to analyze the expression of the intermediate filament (IF), nestin, in odontogenesis. LÄS MER

  7. 5. Isolation and characterization of adult neural stem cells

    Författare :Clas B Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Intermediate filaments; GFAP; nestin; scar formation; regeneration; rodent and human neural stem cells; multipotency.;

    Sammanfattning : Injury to the central nervous system (CNS) is one of man's most handicapping situations resulting in severe functional impairment and in some cases a vegetative state where life is supported artificially. The brain and spinal cord, constituting the CNS, have been viewed for decades as having limited capacity of regeneration with no neurogenesis in the adult. LÄS MER