Sökning: "cytogenetik"

Visar resultat 21 - 25 av 51 avhandlingar innehållade ordet cytogenetik.

  1. 21. Detecting Deletions by Analysis of Genetic Markers in Pedigrees

    Författare :Anna Johansson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytogenetics; Genetik; Genetics; Biologi; genetic marker; pedigree; Protein S deficiency; Biology; PROS1; deletion; null allele; cytogenetik;

    Sammanfattning : A deletion is defined as a missing piece of a chromosome, ranging in size from as small as a single base pair to as much as an entire arm of a chromosome. Deletions can cause diseases, but may also have a neutral effect in the genome. LÄS MER

  3. 22. Molecular studies of pancreatic cancer: Characterization of the transforming growth factor beta signaling pathway

    Författare :Tord Jonson; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SMAD4; PCR; FISH; cytogenetics; chromosome; pancreatic cancer; TGFB signaling; cytogenetik; Genetik; Genetics;

    Sammanfattning : In the present thesis, genetic abnormalities in pancreatic cancer were studied, with special emphasis on alterations of components involved in the transforming growth factor beta (TGFB) signaling pathway. In the first study, fluorescence in situ hybridization and cytogenetic analyses revealed aberrations of chromosome 18 in all 13 pancreatic carcinoma cell lines studied, in particular frequent breaks close to the centromere of chromosome arm 18q. LÄS MER

  4. 23. Classes of DNA associated with telomeres in the chironomids C. pallidivittatus and C. tentans

    Författare :Iréne Kamnert; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; Chironomus; subtelomere; gene conversion; subfamilies; telomere; complex repeats; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : Telomeres in Chironomus consist of long complex tandem DNA repeats, which in C. pallidivittatus have been shown to extend to the extreme end of chromosomes. In C. pallidivittatus the telomeric repeats are present in large blocks, 50-200kb in size, most of them belonging to four major subfamilies. LÄS MER

  5. 24. Linkage maps in studies of genetic variation - examples from Beta vulgaris

    Författare :Thomas Kraft; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytogenetics; Genetics; Beta vulgaris; Linkage maps; genetic variation; Genetik; cytogenetik;

    Sammanfattning : Today, most studies of genetic variation utilise molecular markers, making it possible to detect variation at the DNA level. This has greatly facilitated studies of genetic variation in population and evolutionary genetics, systematics and transmission genetics. LÄS MER

  7. 25. Molecular Phylogenetics of Mammals

    Författare :Morgan Kullberg; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; EST; divergence times; phylogenomics; phylogenetic reconstruction; Mammals; Eutheria; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : In this thesis, the phylogenetic relationships of the Mammalia have been studied at various levels. Different sources of genetic information have been evaluated and used as phylogenetic markers. These include the well-known mitochondrial genome, cDNA from housekeeping genes and expressed sequence tags from nuclear genes. LÄS MER