Sökning: "circulating hormones"
Visar resultat 6 - 10 av 60 avhandlingar innehållade orden circulating hormones.
6. Adipocyte-derived hormones and cardiovascular disease
Sammanfattning : Obesity is increasing globally and related to major changes in lifestyle. This increase is associated with an increased risk of cardiovascular disease (CVD). Knowledge about adipose tissue as a metabolic-endocrine organ has increased during the last few decades. LÄS MER
7. Register-based studies of sex steroid hormones and psychiatric disorders
Sammanfattning : The focus of this thesis is the interplay between sex steroid hormones, psychiatric- and neurodevelopmental disorders and adverse behavioral outcomes. Sex steroid hormones are mostly known for their role in sexual differentiation and reproduction, but have been suggested to be involved the etiology of several psychiatric disorders and in adverse behaviors that show prominent sex differences in prevalence. LÄS MER
8. Microbial regulation of Insulin-like peptide 5 and its implication on metabolism and bariatric surgery
Sammanfattning : The microbial community in our gastrointestinal tract, the gut microbiota, has great impact on our physiology. Particularly, the role for gut microbiota in host health and disease has been associated with modulation of gut hormones which are key players in the regulation of energy homeostasis. LÄS MER
9. Development of GC-HRMS procedures for determination of naturally occuring polar compounds in various environmental applications
Sammanfattning : The overall objectives of this dissertation were to gain further understanding of the two following environmentally significant issues: (i) Determination of natural steroid hormones in blood plasma from perch (Perca fluviatilis) during a reproductive cycle and to evaluate the possibility of using the steroid composition as a biomarker for early signs of endocrine disruptive effects. (ii) Determination of dissolved free amino acids in size resolved airborne particles collected over the Arctic pack ice area (>80°N) in summer and to study their overall relationship with the ocean surface microlayer as a potential source. LÄS MER
10. The insulin-like growth factor system : effects of circulating proteases
Sammanfattning : The insulin-like growth factor-I and -II (IGF-I/-II) are peptide hormones important for growth and metabolism. They stimulate cell proliferation and differentiation and inhibit apoptosis. In addition, they have insulin-like effects on glucose and amino acid metabolism. LÄS MER