Sökning: "chromosome model"

Visar resultat 6 - 10 av 188 avhandlingar innehållade orden chromosome model.

  1. 6. Neurospora tetrasperma from Natural Populations : Toward the Population Genomics of a Model Fungus

    Författare :Pádraic Corcoran; Hanna Johannesson; Sylvain Glemin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neurospora; poulation genetics; genomes; introgression; Evolutionary Genetics; Evolutionär genetik;

    Sammanfattning : The study of DNA sequence variation is a powerful approach to study genome evolution, and to reconstruct evolutionary histories of species. In this thesis, I have studied genetic variation in the fungus Neurospora tetrasperma and other closely related Neurospora species. I have focused on N. LÄS MER

  3. 7. Control of Chromosome and Plasmid Replication in Escherichia coli

    Författare :Jan Olsson; Kurt Nordström; Santanu Dasgupta; Måns Ehrenberg; Anders Lobner-Olesen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Mikrobiologi; Microbiology; Mikrobiologi; mikrobiologi; Microbiology;

    Sammanfattning : Life is cellular. Cells grow and divide to give two new cells; this process is called the cell cycle. The chromosome in a bacterium is replicated into two identical copies before the cell divides. DNA replication is a fundamental process common to all forms of life. LÄS MER

  4. 8. Meiotic chromosome segregation : molecular analysis of the synaptonemal complex

    Författare :Li Yuan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Meiosis is a special type of cell division that produces haploid gametes from diploid parental cells. As such, meiosis stands at the gateway to sexual reproduction in most eukaryotic organisms. During meiosis, a complex, but tightly coordinated series of events occur. Homologous chromosomes come together and pair along their entire length. LÄS MER

  5. 9. Murine plasmacytomagenesis : an experimental model of B-cell neoplasia

    Författare :Santiago C Silva; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :mouse plasmacytomas; chromosomal translocation; chimeric mice; MYC-transgenic mice; ;

    Sammanfattning : A chromosomal translocation which results in the illegitimate activation of the c-myc proto-oncogene by one of the three immunoglobulin (Ig) loci is invariably associated with human Burkitt's Lymphoma (BL), mouse plasmacytoma (MPC) and rat immunocytomas (RIC). In the MPC system a genetic predisposition linked to the BALB/c strain has been suggested. LÄS MER

  7. 10. Of Mice and MYC : Modelling Medulloblastoma

    Författare :Oliver Mainwaring; Fredrik J. Swartling; Charles Eberhart; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medulloblastoma; MYC; Group 3; Cdkn2a; ARF; HSP90; Chromosome 17q; Medicinsk vetenskap; Medical Science; Oncology; Onkologi;

    Sammanfattning : Brain tumours are the leading cause of cancer-related paediatric deaths, with medulloblastoma (MB) being the most common malignant paediatric brain tumour. MB is stratified into four major subgroups – WNT, SHH, Group 3, and Group 4, nomenclature defined by key pathways and drivers involved within each subgroup. LÄS MER