Sökning: "chromatin structure"
Visar resultat 1 - 5 av 108 avhandlingar innehållade orden chromatin structure.
1. Chromatin Structure: Nucleosome Formation and Positioning
Sammanfattning : In all eukaryotic cells the DNA is complexed with a group of highly basic histone proteins forming nucleosomes and higher order chromatin structures. In the nucleosome the DNA is tightly wrapped, almost two turns, around an octamer of histone proteins. LÄS MER
2. DNA-protein complexes : experimental studies of structure and interactions in solution
Sammanfattning : .... LÄS MER
3. Chromatin Remodeling by BRG1 and SNF2H : Biochemistry and Function
Sammanfattning : Chromatin is a highly dynamic, regulatory component in the process of transcription, repair, recombination and replication. The BRG1 and SNF2H proteins are ATP-dependent chromatin remodeling proteins that modulate chromatin structure to regulate DNA accessibility for DNA-binding proteins involved in these processes. LÄS MER
4. The interplay of transcription and chromatin regulation during embryonic development
Sammanfattning : A fascinating aspect of multicellular development is the production of diverse cell types from an identical DNA genome, which depends on the ability to express different complements of genes across space and time. This thesis tries to address how the genome, within the chromatin structure that envelops it, is regulated to direct this complex process. LÄS MER
5. Chromatin and transcriptome-based integrative approaches to profile functional long noncoding RNAs - A computational approach
Sammanfattning : One of the major hallmarks of cancer is aberrant or uncontrollable cell division, which occurs due to a defective cell cycle process. During the synthesis phase (S-phase) of the cell cycle, before cell division or mitosis phase, the DNA in the cell makes a new copy to pass on genetic information to the daughter cells. LÄS MER