Sökning: "breast size"

Visar resultat 6 - 10 av 113 avhandlingar innehållade orden breast size.

  1. 6. Genetic determinants of breast cancer risk

    Författare :Jingmei Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast Neoplasms;

    Sammanfattning : The main purpose of this thesis was to identify genetic risk factors using both hypothesis-based and hypothesis-free approaches. In an attempt to identify common disease susceptibility alleles for breast cancer, we started off with a hypothesis-free approach, and performed a combined analysis of three genome-wide association studies (GWAS), involving 2,702 women of European ancestry with invasive breast cancer and 5,726 controls. LÄS MER

  3. 7. Characterization of Male Breast Cancer : From Molecule to Clinical Outcome

    Författare :Cecilia Nilsson; Marie-Louise Fjällskog; Leif Bergkvist; Thomas Hatschek; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; male breast cancer; immunohistochemistry; prognostic; cyclins; gene expression; genomic profiling; Oncology; Onkologi; Oncology; Onkologi;

    Sammanfattning : The aim of this thesis was to investigate different aspects of male breast cancer (MBC), and to compare these with findings in female breast cancer (FBC). In paper I, a population–based study was performed to investigate possible differences in treatment and outcome between MBC and FBC patients. LÄS MER

  4. 8. DCIS of the breast : aspects on treatment and prognosis

    Författare :Charlotta Wadsten; Malin Sund; Fredrik Wärnberg; Marjut Leidenius; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Breast cancer is the most common cancer form and a leading cause of death in women worldwide. Ductal breast carcinoma in situ (DCIS) is characterized by a proliferation of malignant cells confined within the mammary ducts and is a potential precursor of invasive breast cancer. LÄS MER

  5. 9. Local recurrence after breast conserving surgery in breast cancer

    Författare :Irma Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast Cancer; Breast Conserving Surgery; Radiotherapy; Local Recurrence; Axillary Recurrence; Risk Factors; Distant Metastasis; Cohort Study; Case-Control Study;

    Sammanfattning : The general aim of this thesis was to gain increased insight into the problem of local recurrences after breast conserving surgery for breast cancer. In a population-based cohort of 4,694 women with invasive breast cancer, operated in 1981 to 1990 and followed through 1997, we studied how breast conserving surgery had been adopted into clinical practice. LÄS MER

  7. 10. Sentinel Node in Clinical Practice : Implications for Breast Cancer Treatment and Prognosis

    Författare :Yvette Andersson; Leif Bergkvist; Jan Frisell; Jana de Boniface; Robert Mansel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; sentinel node; micrometastases; survival; non-sentinel node metastases;

    Sammanfattning : The introduction of sentinel lymph node biopsy (SLNB) has conveyed several new issues, such as the risk of false negativity, long-term consequences, the prognostic significance of micrometastases and whether ALND can be omitted in sentinel lymph node- (SLN) positive patients.Archived SLN specimens from 50 false negative patients and 107 true negative controls were serially sectioned and stained with immunohistochemistry. LÄS MER