Sökning: "Jana de Boniface"

Hittade 2 avhandlingar innehållade orden Jana de Boniface.

  1. 1. Sentinel Node Biopsy in Breast Cancer : Clinical and Immunological Aspects

    Författare :Jana de Boniface; Leif Bergkvist; Annika Håkansson; Omgo Nieweg; Uppsala universitet; []
    Nyckelord :Surgery; breast cancer; tumour immunology; sentinel node biopsy; CD3-zeta; CD28; Kirurgi;

    Sammanfattning : The most important prognostic factor in breast cancer is the axillary lymph node status. The sentinel node biopsy (SNB) is reported to stage the axilla with an accuracy > 95 % in early breast cancer. Tumour-related perturbation of T-cell function has been observed in patients with malignancies, including breast cancer. LÄS MER

  2. 2. Sentinel Node in Clinical Practice : Implications for Breast Cancer Treatment and Prognosis

    Författare :Yvette Andersson; Leif Bergkvist; Jan Frisell; Jana de Boniface; Robert Mansel; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; sentinel node; micrometastases; survival; non-sentinel node metastases;

    Sammanfattning : The introduction of sentinel lymph node biopsy (SLNB) has conveyed several new issues, such as the risk of false negativity, long-term consequences, the prognostic significance of micrometastases and whether ALND can be omitted in sentinel lymph node- (SLN) positive patients.Archived SLN specimens from 50 false negative patients and 107 true negative controls were serially sectioned and stained with immunohistochemistry. LÄS MER