Sökning: "amytrophic lateral sclerosis"

Hittade 2 avhandlingar innehållade orden amytrophic lateral sclerosis.

  1. 1. Epidemiologic studies of amytrophic lateral sclerosis

    Författare :Fang Fang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Amyotrophic lateral sclerosis; association; bone turnover; early life exposure; familial aggregation; incidence; lead exposure; relative risk; temporal trend;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. The causes of ALS remain largely unknown more than 140 years after the disease was first described. LÄS MER

  3. 2. Molecular mechanisms underlying morphological effects of protein kinase C under normal conditions and cellular stress

    Författare :Lovisa Sunesson; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; amytrophic lateral sclerosis; PABPC1; IGF2BP3; G3BP2; peripherin; C1 domain; protein-protein-interactions; Protein kinase C; neurite outgrowth;

    Sammanfattning : The protein kinase C (PKC) family of serine/threonine kinases consists of 10-15 members. The PKC isoforms have central roles in many essential cellular processes, including proliferation, apoptosis, differentiation, cytoskeletal changes, and migration. LÄS MER