Sökning: "peripherin"
Hittade 5 avhandlingar innehållade ordet peripherin.
1. Molecular mechanisms underlying morphological effects of protein kinase C under normal conditions and cellular stress
Sammanfattning : The protein kinase C (PKC) family of serine/threonine kinases consists of 10-15 members. The PKC isoforms have central roles in many essential cellular processes, including proliferation, apoptosis, differentiation, cytoskeletal changes, and migration. LÄS MER
2. Phenotypes and genotypes in families with hereditary tapetoretinal degenerations
Sammanfattning : The purpose of the study was to characterise the phenotype with emphasis on electroretinography in four different types of hereditary retinal degeneration and to correlate it to a genotype when possible. Two methods were used: full-field electroretinography for objective assessment of retinal function and mutation screening of blood samples for detection of gene alterations. LÄS MER
3. Stem cell in-vitro strategies for the induction of sensory neurons for inner ear cell therapy
Sammanfattning : The cochlea, a part of the auditory system, is a complex structure consisting of several different types of cells including hair cells and spiral ganglion neurons. In mammals, the regenerative potential of hair cells and spiral ganglion neurons is lost soon after the birth and damage to any of these cells causes sensorineural hearing loss. LÄS MER
4. Neuroprotection and axonal regeneration after peripheral nerve injury
Sammanfattning : Following microsurgical reconstruction of injured peripheral nerves, severed axons are able to undergo spontaneous regeneration. However, the functional result is always unsatisfactory with poor sensory recovery and reduced motor function. LÄS MER
5. Directed differentiation of adult neural stem cells for cell therapy in the nervous system
Sammanfattning : The emergence of neural stem cell research has raised hopes for cell therapy of neurological disorders. Insight into the normal mechanisms of neural stem cell fate specification and differentiation is a prerequisite for the development of safe and efficient clinical applications. LÄS MER