Sökning: "G3BP2"

Hittade 3 avhandlingar innehållade ordet G3BP2.

1. 1. Molecular mechanisms underlying morphological effects of protein kinase C under normal conditions and cellular stress

   Författare :Lovisa Sunesson; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; amytrophic lateral sclerosis; PABPC1; IGF2BP3; G3BP2; peripherin; C1 domain; protein-protein-interactions; Protein kinase C; neurite outgrowth;

   Sammanfattning : The protein kinase C (PKC) family of serine/threonine kinases consists of 10-15 members. The PKC isoforms have central roles in many essential cellular processes, including proliferation, apoptosis, differentiation, cytoskeletal changes, and migration. LÄS MER

3. 2. Regulation of cellular growth and identification of stromal gene signatures in breast cancer

   Författare :Sofia Winslow; Avdelningen för translationell cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; cellular stress; proliferation; PKCα; G3BP; PMP22; miR-34c; gene expression profiles; stroma;

   Sammanfattning : Normal tissue is tightly controlled to keep a balance between reproduction and elimination of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. LÄS MER

4. 3. Alphavirus-host interactions : how to unravel the proviral activity of G3BP

   Författare :Benjamin Götte; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The genus Alphavirus belongs to the virus family Togaviridiae, a group of arthropod-borne enveloped RNA viruses with single-stranded, positive-sense genome. Members of this genus can be found worldwide and are geographically distinguished into Old World and New World alphaviruses. LÄS MER