Sökning: "allogeneic stem cell transplantation"

Visar resultat 11 - 15 av 97 avhandlingar innehållade orden allogeneic stem cell transplantation.

1. 11. Cytokine production in allogeneic haematopoietic stem-cell transplantation patients

   Författare :Mats Remberger; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Severe immunological complications may occur after haematopoietic stem-cell transplantation (HSCT). These include acute graft-versus-host disease (GVHD), veno-occlusive disease of the liver (VOD) and severe infections. LÄS MER

3. 12. Cell and gene therapy for blood disorders. Modeling of novel treatment strategies for Gaucher type 1 disease and Diamond-Blackfan anemia in mice

   Författare :Maria Dahl; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gaucher disease; lentiviral vectors; gene therapy; Diamond-Blackfan anemia; hematopoietic stem cells; bone marrow transplant; Schlafen-2;

   Sammanfattning : Gaucher disease type 1 (GD type 1) and Diamond-Blackfan anemia (DBA) are rare genetic disorders affecting the hematopoietic system and routinely treated by administration of drugs with variable clinical efficacy. Though effective in alleviating disease symptoms in large cohorts of patients, these treatment options have the major drawback of being non-curative. LÄS MER

4. 13. Vaccine responses after chemotherapy or stem cell transplantation in patients with hematological malignancies

   Författare :Sigrun Einarsdottir; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vaccination; chemotherapy; stem cell transplantation; antibodies; tetanus; diphtheria; polio; Tick-borne encephalitis TBE ; SARS-CoV-2;

   Sammanfattning : The prevention of infections in patients with hematological malignancies is important given the inherent immune deficiency associated with these diseases and the immunosuppressive effects of treatment. This thesis investigated the efficacy of vaccines against various pathogens among patients with hematological disease receiving chemotherapy or stem cell transplantation, including the longevity of vaccine responses. LÄS MER

5. 14. Graft-versus-Host Disease: Eosinophils, Chimerism and Clinical Features in Patients Undergoing Allogeneic Hematopoietic Stem Cell or Multivisceral Transplantation

   Författare :Julia Cromvik; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; graft-versus-host disease; eosinophilic granulocyte; intestinal transplantation; multivisceral transplantation; chimerism analysis;

   Sammanfattning : Abstract Graft-versus-host disease (GVHD) is a potentially severe complication that may develop after allogeneic hematopoietic stem cell transplantation (HSCT). It can also occur after transplantation with isolated intestinal grafts or after multivisceral transplantation (MVTX). GVHD is difficult to diagnose. LÄS MER

7. 15. Mucositis Prevention for Patients Receiving High Dose Chemotherapy and Stem Cell Transplantation : Preventive Strategies - There is Always More to do

   Författare :Anncarin Svanberg; Gunnar Birgegård; Kerstin Öhrn; Sharon Elad; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oral mucositis; stem cell transplantion; oral cryotherapy; cooling; cytokine IL-6;

   Sammanfattning : The aim of this thesis was to investigate oral cryotherapy (OC) as prophy-laxis against oral mucositis (OM) in patients given high-dose chemotherapy for stem cell transplantation (SCT). A new mouth rinse device was tested for possible additive effect to OC.For study I-III, 78 patients were randomised to OC or standard oral care (SOC). LÄS MER