Sökning: "Tomas McKenna"

Hittade 2 avhandlingar innehållade orden Tomas McKenna.

  1. 1. Epithelial stem cells In Hutchinson-Gilford progeria syndrome

    Författare :Tomás McKenna; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Hutchinson-Gilford progeria syndrome (HGPS) and restrictive dermopathy (RD) are two rare genetic disorders that affect children. Complications from cardiovascular disease, including atherosclerosis, are the most common cause of death in HGPS, which occurs at around 13 years of age. LÄS MER

  2. 2. Oxidative stress on mammalian cell cultures during recombinant protein expression

    Författare :Tomás McKenna; Carl-Fredrik Mandenius; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : When the cell is under stress arising from oxidation, heat, infection, toxic contamination or any other stressful condition, proteins may unfold and expose residues in their structure that under normal physiological conditions are hidden and shielded from chemical reactions.In this licentiate thesis the effects of general oxidative stress on the production of recombinant protein by mammalian cells are considered. LÄS MER