Sökning: "T-Lymphocytes pathology"
Visar resultat 6 - 8 av 8 avhandlingar innehållade orden T-Lymphocytes pathology.
6. The immortalization process of T cells : with focus on the regulation of telomere length and telomerase activity
Sammanfattning : Cellular immortalization is a major hallmark of cancer and is a multi-step process that requires numerous cell-type specific changes, including inactivation of control mechanisms and stabilization of telomere length. The telomeres at the chromosome ends are essential for genomic stability, and limit the growth potential of most cells. LÄS MER
7. Immunological Mechanisms and Natalizumab Treatment in Multiple Sclerosis : Studies on lymphocytes, inflammatory markers and magnetic resonance spectroscopy
Sammanfattning : Background: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating disease of the central nervous system (CNS), and a frequent cause of neurological disability among young adults. In addition to focal inflammatory demyelinated lesions, diffuse white matter pathology as well as a neurodegenerative component with accumulating axonal damage and gliosis have been demonstrated and contribute to MS disease characteristics. LÄS MER
8. Regulation of T cell effector functions in the intestinal mucosa
Sammanfattning : T lymphocytes are a critical cellular component of the adaptive immune response. They are generated in the thymus from bone marrow derived progenitors, where they undergo commitment to the T cell lineage and differentiate and mature into naïve CD4+ and CD8+ T cells. LÄS MER