Sökning: "Septic shock"

Visar resultat 11 - 15 av 73 avhandlingar innehållade orden Septic shock.

  1. 11. Adrenomedullin in sepsis

    Författare :Oscar Lundberg; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; biomarker; adrenomedullin; endothelin-1; high-sensitivity troponin t; intensive care unit; emergency department; septic shock;

    Sammanfattning : AbstractBackgroundSepsis is a syndrome difficult to diagnose and stratify. The epidemiology of sepsis and consistency of criteria fulfillment with diagnosis coding in Swedish intensive care units (ICU) are largely unknown. Biomarkers can be of help to understand pathophysiology, identify clusters within sepsis and to individualize treatment. LÄS MER

  2. 12. Antibiotic-induced Bacterial Toxin Release – Inhibition by Protein Synthesis Inhibitors

    Författare :Gunilla Hjerdt-Goscinski; Jan Sjölin; Monica Lundholm; Inga Odenholt; Ingrid Nilsson-Ehle; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Endotoxin; LPS; exotoxin; SpeA; penicillin-binding protein; aminoglycosides; clindamycin; β-lactam antibiotics; severe sepsis; septic shock; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

    Sammanfattning : Toxic products, such as endotoxin from the gram-negative and exotoxin from the gram-positive bacteria, are the most important initiators of the inflammatory host response in sepsis. In addition to antibacterial treatment, numerous attempts have been made to interfere with the exaggerated proinflammatory cascade initiated by the toxins. LÄS MER

  3. 13. Heparin-binding protein and organ failure in critical illness

    Författare :Jonas Tydén; Joakim Johansson; Magnus Hultin; Jakob Walldén; Sören Berg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparin-binding protein; Critical care; Shock; Acute respiratory distress syndrome; Acute kidney injury; Ventilator induced lung injury; Renal clearance; Anaesthesiology; anestesiologi;

    Sammanfattning : Background: For patients severely ill enough to require care in an intensive care unit (ICU), both the disease itself (e.g. bacteria in the blood in sepsis or fractures after trauma) and effects of the immune system can cause circulatory, pulmonary, or renal dysfunction. Leukocytes play a dominant role in the immune system. LÄS MER

  4. 14. Optimizing fluid therapy in the hemodynamically unstable patient

    Författare :Anja Lindén; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Septisk chock; Vätsketerapi; Icke-resusciteringsvätska; Hemodynamisk instabilitet; Preload responsiveness; Blodvolym; Septic shock; Fluid therapy; Non-resuscitation fluids; Hemodynamic instability; Blood volume;

    Sammanfattning : .... LÄS MER

  5. 15. On bioenergetic failure in septic shock : lactate kinetics and mitochondrial respiration

    Författare :Jonathan Grip; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Septic shock, a dysregulated immune response to an infection, is a major cause of mortality and morbidity in patients treated in intensive care units (ICUs). The cause of the organ dysfunction seen in sepsis is still not fully elucidated, but a disrupted intracellular metabolism, a bioenergetics failure, has been suggested as a possible mechanism. LÄS MER