Sökning: "Heparin-binding protein"

Visar resultat 1 - 5 av 45 avhandlingar innehållade orden Heparin-binding protein.

1. 1. Heparin-binding protein and organ failure in critical illness

   Författare :Jonas Tydén; Joakim Johansson; Magnus Hultin; Jakob Walldén; Sören Berg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparin-binding protein; Critical care; Shock; Acute respiratory distress syndrome; Acute kidney injury; Ventilator induced lung injury; Renal clearance; Anaesthesiology; anestesiologi;

   Sammanfattning : Background: For patients severely ill enough to require care in an intensive care unit (ICU), both the disease itself (e.g. bacteria in the blood in sepsis or fractures after trauma) and effects of the immune system can cause circulatory, pulmonary, or renal dysfunction. Leukocytes play a dominant role in the immune system. LÄS MER

3. 2. On the prognostic value of Heparin-binding protein in Sepsis

   Författare :Jonas Tverring; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; Biomarker; Heparin-binding protein HBP ; Diagnostic accuracy; added value;

   Sammanfattning : Sepsis causes major morbidity and mortality worldwide. There is wide consensus that biomarkers have an important role in sepsis research and patient care. Heparin-binding protein (HBP) is a neutrophil-derived, proinflammatory and vascular permeability-inducing protein and a promising novel sepsis biomarker. LÄS MER

4. 3. Studies on Heparin Binding protein in bacterial infections

   Författare :Adam Linder; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Infectious diseases remain a major health problem, where sepsis and other severe bacterial infections are common causes of morbidity and mortality, and are associated with high costs for the community. The importance of early and appropriate treatment of sepsis and severe bacterial infections has been underlined by many and since sepsis is more prevalent and has a higher mortality rate than for instance acute myocardial infarction, there is a need for improvement. LÄS MER

5. 4. Streptococcus pyogenes - a manipulator of human defences

   Författare :Fredrik Kahn; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pyogenes; M protein; neutrophils; platelets; platelet-neutrophil complexes; fibrinogen; IgG; abscess; venous thrombosis; heparin binding protein; thrombocytopenia;

   Sammanfattning : Streptococcus pyogenes is a major human pathogen with more than 500 000 casualties annually of which at least 163 000 are due to invasive infections. The remainder is due to post-streptococcal complications with rheu¬matic heart disease constituting the majority. S. LÄS MER

7. 5. Bacterial virulence or exorbitant host response? On innate immunity against the streptococcal M1 protein

   Författare :Sandra Persson; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skin infection; Streptococcus pyogenes; M1 protein; Innate Immunity; Host response; Virulence factor; Neutrophil recruitment; Heparin-binding protein HBP ; Leptospirosis;

   Sammanfattning : Bacterial infection is inevitable throughout a lifetime. What differs between mild andserious infections is the pathogen responsible and how the host immune systemresponds to it. A fundamental role to prevent infection is a proper physical barrier such as the skin and mucosa. LÄS MER