Sökning: "Robert Kronstrand"

Hittade 5 avhandlingar innehållade orden Robert Kronstrand.

  1. 1. Analytical and Toxicological Aspects of Drug Incorporation into Human Hair

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Robert Kronstrand; Pascal Kintz; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : The overall purpose of this thesis was to develop analytical methods for the determination of drugs and melanin content of human hair for practical use in forensic and clinical toxicology. The thesis consists of five papers, two of which are controlled single dose studies where codeine or selegiline were administered to healthy volunteers. LÄS MER

  2. 2. Organelle movement in melanophores: Effects of Panax ginseng, ginsenosides and quercetin

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Therese Eriksson; Rolf Andersson; Samuel Svensson; Ingemar Lundström; Robert Kronstrand; Per Hammarström; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melanophores; Panax ginseng; ginsenosides; quercetin; organell anterograde transport; endothelin-3; mitogen activated protein kinase; protein kinase C; MEDICINE; MEDICIN;

    Sammanfattning : Panax ginseng is a traditional herb that has been used for over 2000 years to promote health and longevity. Active components of ginseng include ginsenosides, polysaccharides, flavonoids, polyacetylenes, peptides, vitamins, phenols and enzymes, of which the ginsenosides are considered to be the major bioactive constituents. LÄS MER

  3. 3. Forensic Toxicological Aspects of Tramadol Focus on Enantioselective Drug Disposition and Pharmacogenetics

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Pernilla Haage; Fredrik Kugelberg; Robert Kronstrand; Espen Molden; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : One of the most difficult parts in forensic toxicology is to interpret obtained drug concentrations. Was it therapeutic, toxic or even lethal to the particular individual that the blood sample was drawn from? Concentrations of opioid drugs are especially difficult to interpret, because of large interindividual differences in innate and acquired tolerance. LÄS MER

  4. 4. Stability of zopiclone in whole blood Studies from a forensic perspective

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Gunnel Nilsson; Robert Kronstrand; Johan Ahlner; Fredrik Kugelberg; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : Bio‐analytical results are influenced by in vivo factors like genetic, pharmacological and physiological conditions and in vitro factors like specimen composition, sample additives and storage conditions. The knowledge of stability of a drug and its major metabolites in biological matrices is very important in forensic cases for the interpretation of analytical results. LÄS MER

  5. 5. Zopiclone degradation in biological samples Characteristics and consequences in forensic toxicology

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Gunnel Nilsson; Robert Kronstrand; Fredrik C. Kugelberg; Johan Ahlner; Mikael Hedeland; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Bio-analytical results are influenced by in vivo factors such as genetics, pharmacological and physiological conditions and in vitro factors such as specimen composition, sample additives and storage conditions. Zopiclone (ZOP) is a short-acting hypnotic drug (Imovane®) used for treatment of insomnia. LÄS MER