Sökning: "Pulmonary arterial hypertension"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Pulmonary arterial hypertension.

  1. 1. Pulmonary hypertension. Clinical and pathophysiological studies

    Författare :Nedim Selimovic; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Pulmonary hypertension; Echocardiography; Right heart catheterisation; Pulmonary vascular resistance; Pulmonary function tests; Lung transplantation; Mortality on the waiting list; Vascular remodelling; Growth substances; Inflammation; Endothelin;

    Sammanfattning : Pulmonary hypertension (PH) is a common abnormality, most often associated with various cardiopulmonary diseases. Pulmonary arterial hypertension (PAH) is a devastating pulmonary vascular disease characterised by the proliferation of endothelial, smooth-muscle cells and fibroblasts. LÄS MER

  2. 2. Pulmonary Hypertension and the Nitric Oxide System

    Författare :Dan Henrohn; Gerhard Wikström; Ulla Lindqvist; John Pernow; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pulmonary hypertension; nitric oxide; ADMA; arginine; nitrate; nitrite; vardenafil; beetroot juice; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Pulmonary hypertension (PH) is a pathophysiological state associated with several medical conditions, leading to progressive rise in pulmonary vascular resistance (PVR) and right ventricular failure. The clinical PH classification encompasses five main World Health Organization (WHO) groups; pulmonary arterial hypertension (PAH), PH due to left heart disease, PH due to lung diseases and/or hypoxia, chronic thromboembolic PH, and PH with unclear multifactorial mechanisms. LÄS MER

  3. 3. Plasma biomarkers in pulmonary arterial hypertension diagnosis, treatment response and risk stratification - utilizing Lund Cardio Pulmonary Register

    Författare :Habib Bouzina; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pulmonary arterial hypertension; Plasma biomarkers; Risk stratification; Treatment response;

    Sammanfattning : .... LÄS MER

  4. 4. Pulmonary hypertension : the role and place of PDGF

    Författare :Philip Tannenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Pulmonary hypertension is a severe condition, leading to right heart dysfunction and preterm death. For pulmonary arterial hypertension (PAH), a disease group in which the primary pathology resides within the pulmonary pre-capillary vessels, several specific therapies are in clinical use, but unfortunately the prognosis is still grim. LÄS MER

  5. 5. Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstriction

    Författare :Peter Holm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; bosentan; BMS-182874; ; BQ-123; BQ-788; endothelin; endothelium; hypoxia; hypoxic pulmonary vasoconstriction; pulmonary hypertension; receptor antagonism; TBC 11251.;

    Sammanfattning : Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstriction Peter Holm A number of substances originating from the pulmonary endothelium have recently been found to be involved in the regulation of pulmonary vascular tone. Accumulating evidence suggests that endothelial dysfunction contributes to pulmonary hypertension, an important clinical problem often associated with hypoxemia. LÄS MER