Sökning: "Pulmonary arterial hypertension"

Visar resultat 6 - 10 av 26 avhandlingar innehållade orden Pulmonary arterial hypertension.

  1. 6. Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstriction

    Författare :Peter Holm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :bosentan; BMS-182874; ; BQ-123; BQ-788; endothelin; endothelium; hypoxia; hypoxic pulmonary vasoconstriction; pulmonary hypertension; receptor antagonism; TBC 11251.;

    Sammanfattning : A number of substances originating from the pulmonary endothelium have recently been found to be involved in the regulation of pulmonary vascular tone. Accumulating evidence suggests that endothelial dysfunction contributes to pulmonary hypertension, an important clinical problem often associated with hypoxemia. LÄS MER

  3. 7. Skin fibrosis, internal organ involvement and auto antibodies in systemic sclerosis: longitudinal development and impact on survival

    Författare :Roger Hesselstrand; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; proteoglycan; pulmonary hypertension; organ involvement; auto antibodies; survival; systemic sclerosis; prognosis;

    Sammanfattning : Systemic sclerosis (SSc) is a connective tissue disease with a highly variable prognosis. Since new treatment strategies are emerging, there is a need for prognostic markers in order to help allocate patients to the optimal treatment. LÄS MER

  4. 8. Nitric Oxide Exchange in Central and Peripheral Airways : Determinants in Health and Respiratory Disease

    Författare :Andrei Malinovschi; Christer Janson; Kjell Alving; Lena Holm; Elisabeth Bel; Uppsala universitet; []
    Nyckelord :exhaled nitric oxide; alveolar NO; bronchial NO flux; extended NO analysis; asthma; smoking; snus; IgE-sensitization; pharyngo-oral tract; nitrate; nitrite; pulmonary hypertension;

    Sammanfattning : Background: Exhaled nitric oxide (NO) is a marker of eosinophilic steroid-sensitive inflammation in the airways of patients with respiratory disease. Moreover, information about the localization of inflammation in the respiratory tree is obtained by estimates of bronchial and alveolar contributions to exhaled NO. LÄS MER

  5. 9. Obstructive sleep apnea and cardiovascular morbidity

    Författare :Yüksel Peker; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstructive sleep apnea; cardiovascular; hypertension; coronary artery disease; hospitalization; cost utility; morbidity; mortality; secondary prevention; angiotensin II; CPAP;

    Sammanfattning : Obstructive sleep apnea (OSA) affects 24 % of middle-aged men and 9 % of women in USA but the treatment criterion, daytime sleepiness is reported by 17 and 22 % of these subjects, respectively. Some previous studies have suggested an association between OSA and cardiovascular disease (CVD), but the conclusions have been conflicting due to co-existing traditionally recognized risk factors. LÄS MER

  7. 10. Diagnostic and prognostic value of cardiac magnetic resonance in patients with pulmonary hypertension

    Författare :Anthony Lindholm; Lund Klinisk fysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Pulmonary arterial hypertension (PAH) is a rare disease with poor prognosis. The symptoms are often unspecific, which can lead to delayed diagnosis. LÄS MER