Sökning: "Potentiation"

Visar resultat 16 - 20 av 84 avhandlingar innehållade ordet Potentiation.

  1. 16. Transport and release of insulin granules during biphasic insulin secretion

    Författare :Rosita Ivarsson; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; granule transport; Myosin 5a; Cyclic AMP; NADPH; Motor protein; Insulin secretion; Cytoskeleton;

    Sammanfattning : Glucose-evoked insulin secretion exhibits two phases: The first phase represents exocytosis of insulin granules situated at the plasma membrane, whereas the second phase reflects insulin release from granules continuously recruited to the plasma membrane. This thesis investigates different aspects of phasic insulin secretion, with the specific aims to elucidate the possible contribution of insulin granule transport, as well as to study the influence of the nucleotides cAMP and NADPH to this process. LÄS MER

  3. 17. Biological risk factors for crime : Adverse perinatal events and psychophysiology

    Författare :Sofi Oskarsson; Catherine Tuvblad; Henrik Larsson; Marianne Kristiansson; Örebro universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Biological Risk Factors; Crime; Criminal Offender; Biological Criminology; Adverse Perinatal Events; Psychophysiology; Psychopathy;

    Sammanfattning : Biological risk factors for crime have been largely neglected within main-stream criminology. However, a large body of research has over the past few decades converged on the conclusion that it is important to consider biological risk factors for crime, as they may help to inform theory and etiology. LÄS MER

  4. 18. Molecular mechanisms of metal toxicity in neuronal cells

    Författare :Annamaria Rossi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Modification of signal transduction by toxic agents can affect cell metabolism and physiological activity, impair cell capacity to adequately respond to hormones and growth stimuli and consequently compromise cell survival. This thesis describes studies on the interactions between toxic metals, at concentrations comparable to environmental exposure, and Ca2+ signalling in neuronal cells. LÄS MER

  5. 19. Short- and long-term neuronal plasticity in hippocampal CA1 region of rat

    Författare :Fen-Sheng Huang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glutamate; hippocampus; plasticity; synapse; LTP; LTD; AMPA; NMDA;

    Sammanfattning : The brain is highly plastic, displaying both short- and long-term changes, resulting from developmental processes as well as learning and memory. Moreover, short-term plasticity such as paired pulse facilitation and depression (PPF, PPD) have long been used to monitor the presynaptic versus postsynaptic changes occurring during more lasting processes such as long-term potentiation and depression (LTP, LTD). LÄS MER

  7. 20. Investigation on Pre- and Postsynaptic Ca2+ Signaling in Neuronal Model Systems

    Författare :Jelena Krjukova; Åkerman Karl; Kukkonen Jyrki; Rydqvist Bo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; calcium; neurotransmitter release; nicotine; depolarization; G-protein coupled receptor; muscarinic; phospholipase C; m-3M3FBS; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : Communication between neuronal and non-neuronal is called volume transmission when the released neurotransmitter (NT) acts via diffusion and affects several target cells. Both the neurosecretory and postsynaptic cell responses are linked to [Ca2+]i elevations. LÄS MER