Sökning: "Plasmacytoid dendritic cell"

Visar resultat 16 - 20 av 34 avhandlingar innehållade orden Plasmacytoid dendritic cell.

  1. 16. Studies of the tumor microenvironment : Local and systemic effects exerted by the cross-talk between tumor and stroma cells in pancreatic cancer

    Författare :Vegard Tjomsland; Marie Larsson; Arne Östman; Linköpings universitet; []
    Nyckelord :Pancreatic cancer; cancer associated fibroblasts; dendritic cells; IL-1alpha; tumor microenvironment; inflammation; bukspottkörtelcancer; Bukspyttkjertel kreft; MEDICINE; MEDICIN;

    Sammanfattning : Pancreatic cancer is one of the most lethal cancers and despite all research efforts the last 50 years, there are still no effective therapy for this terrible disease. Until quite recently most research in the field of pancreatic duct adenocarcinoma (PDAC) was focused on the tumor cells and mechanisms essential for their proliferation and survival. LÄS MER

  3. 17. Studies of human dendritic cells in the skin after antigen exposure

    Författare :Emily Bond; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Dendritic cells (DCs) act at the interface of innate and adaptive immunity. They are capable of inducing strong effector immune responses to invading pathogens, but also exert important functions in the maintenance of tolerance. LÄS MER

  4. 18. Monocytes and dendritic cells : roles during human influenza and hantavirus infections

    Författare :Sindhu Vangeti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Viruses infect a vast majority of the other species on the planet and rarely leave the host undamaged. Most human viruses need to infect an individual to replicate and disseminate, and must contend with the full force of the human immune system. LÄS MER

  5. 19. Studies on dendritic cells and cytokines in inflammatory diseases of the central nervous system

    Författare :Mikhail Pashenkov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is characterised by chronic inflammation in the central nervous system (CNS), which results in primary demyelination, axonal loss and neurological deficit. MS is believed to be mediated by myelin antigen-reactive T cells, which after priming in the periphery enter the CNS and initiate demyelination. LÄS MER

  7. 20. Systemic and local regulation of experimental arthritis by IFN-α, dendritic cells and uridine

    Författare :Sudeep Chenna Narendra; Mattias Magnusson; Srinivas Uppugunduri; Alf Kastbom; Natacha Bessis; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In this thesis, we have studied the immunological processes of joint inflammation that may be targets for future treatment of patients with arthritis. We focus on the immune-modulating properties of interferon-α (IFN-α) and uridine in experimental arthritis. LÄS MER