Sökning: "Pityrosporum orbiculare"

Hittade 3 avhandlingar innehållade orden Pityrosporum orbiculare.

  1. 1. Immunological mechanisms in atopic dermatitis : clinical and experimental studies

    Författare :Maria Tengvall Linder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atopic dermatitis; Cyclosporin A; cytokines; eosinophils; lgE; lgE receptors; Pityrosporum orbiculare; patch test; skin biopsy specimens; T cells;

    Sammanfattning : The aim of the study was to investigate immunological mechanisms in atopic dermatitis. Serum IgE levels are elevated in 80% of atopic dermatitis patients and CD4+ T cells and environmental allergens are known to be of importance in the pathogenesis of the disease. LÄS MER

  3. 2. Identification and characterization of allergen components of the opportunistic yeast Malassezia furfur

    Författare :Arezou Zargari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :allergen; atopic dermatitis; baculovirus; Candida albicans; CAP RAST; cDNA; confocal laser scanning microscopy; Escherichia coli; IgE; Malassezia furfur; monoclonal antibody; Pityrosporum orbiculare; recombinant allergen; yeast.;

    Sammanfattning : The yeast Malassezia furfur (Pityrosporum orbiculare) is a member of the human normal skin microflora. It has been suggested that this yeast plays an important role in the pathogenesis of atopic dermatitis (AD). In 40-65% of patients with AD anti-M. furfur activity has been shown with skin tests and/or specific IgE serology. LÄS MER

  4. 3. Analysis of human epidermal Langerhans' cells and allergens with confocal laser scanning microscopy

    Författare :Axel Emilson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :3-D analysis; allergen; allergic contact dermatitis; basal cellcarcinoma; Bet v I; birch; confocal laser scanning microscopy; epidermis; HLA-DR; image analysis; invariant chain; irritant contact dermatitis; Langerhans cell; occlusion; P. orbiculare;

    Sammanfattning : The aim of the thesis was to explore confocal laser scanning microscopy (CLSM) as a tool for 1) quantitative and 3-dimensional (3-D) analysis of the human antigen-presenting Langerhans' cell (LC) in epidermis and 2) for localization of allergens in yeast cells and in birch pollen. Epidermal LCs were investigated after occlusion with patch tests and in basal cell carcinoma (BCC) skin. LÄS MER