Sökning: "Patric Stenberg"
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1. Computational models for the prediction of intestinal membrane permeability
Sammanfattning : Lead compounds generated in high-throughput drug discovery programs often have unfavorable biopharmaceutical properties, resulting in a low success rate for such drug candidates in clinical development. Efficient and reliable methods that predict biopharmaceutical properties, such as intestinal permeability and solubility are therefore required in order to reduce the attrition rate during development of these compounds. LÄS MER
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