Sökning: "PMNs"

Visar resultat 6 - 10 av 24 avhandlingar innehållade ordet PMNs.

  1. 6. Pathogenic Neisseria infections of human neutrophils and epithelial cells : focusing on host responses and immune evasion

    Författare :Niklas Söderholm; Helena Aro; Thomas Rudel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; Neisseria gonorrhoeae; Neutrophils; PMN; Epithelial cells; Polarized cells; Type IV pili; Adherence; Cell cycle; DNA damage; Lactobacillus; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : N. meningitidis and N. gonorrhoeae are obligate human pathogens that colonize mucosal surfaces and are often carried asymptomatically. These bacteria have developed adhesive structures that promote adherence to host cells and efficient colonization of new hosts. LÄS MER

  3. 7. Acute skeletal muscle ischemia and reperfusion in the rat : The role of leukocytes and the effect of hyperbaric oxygen on microcirculation and metabolism during reperfusion

    Författare :Allan Sirsjö; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Much experimental work in recent years seems to indicate that reperfusion after long periods of ischemia can damage tissue. Suggested factors of importance are accumulation of polymorphonuclear leukocytes (PMNs) and production of reactive oxygen metabolites (ROMs). LÄS MER

  4. 8. The role of endothelin during myocardial ischaemia and reperfusion : pathophysiological mechanisms and interactions with nitric oxide

    Författare :Adrian T Gonon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ischaemia; reperfusion injury; myocardium; infarct size; endothelium; endothelin; endothelin receptor; nitric oxide; nitric oxide synthase; polymorphonuclear leukocytes; myeloperoxidase; pig; rat;

    Sammanfattning : Acute myocardial infarction followed by reperfusion results in accelerated necrosis of irreversibly injured myocytes as well as induction of lethal injury to reversibly injured cells. Polymorphonuclear leukocytes (PMNs) are major participants in the reperfusion-initiated inflammation. LÄS MER

  5. 9. Studies on leukotriene B4 and alarmins in inflammatory responses

    Författare :Min Wan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Leukotriene B4 (LTB4) is a potent proinflammatory lipid mediator that is involved in host defense and inflammatory diseases, such as atherosclerosis. LL-37 and heparin binding protein (HBP) are cationic antimicrobial polypeptides, which belong to the alarmin family known to promote innate and adaptive immune reactions in response to tissue infection or injury. LÄS MER

  7. 10. Expression and regulation of antimicrobial peptides in mucosal immunity

    Författare :Andreas Cederlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antimicrobial polypeptides (AMPs) are effector molecules of the innate immune defense. AMPs are mainly expressed in epithelial cells and immune cells, providing the first line of defense to infection as direct antimicrobials. In addition, many AMPs display immunomodulatory functions in both the adaptive and innate immune system. LÄS MER