Sökning: "P. aeruginosa"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden P. aeruginosa.

  1. 1. Treatment of Pseudomonas aeruginosa using immunoglobulin Y : A porcine experimental model of ventilator-associated pneumonia and septic shock caused by P. aeruginosa

    Författare :Alexander Otterbeck; Miklós Lipcsey; Michael Haney; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Background: Ventilator associated pneumonia (VAP) caused by Pseudomonas aeruginosa is a common cause of morbidity and mortality in patients treated in the intensive care unit. The spread of pathogens with anti-microbial resistance mandates the investigation of novel therapeutic strategies. We hypothesized that specific polyclonal anti-P. LÄS MER

  3. 2. Cellular targets of Pseudomonas aeruginosa toxin Exoenzyme S

    Författare :Maria Henriksson; Bengt Hallberg; Lars Rönnstrand; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Pseudomonas aeruginosa; ADP-ribosylation; GAP; Ras superfamily; NAD; ExoS; 14-3-3; Cellbiologi; Cell biology; Cellbiologi; molecular cell biology; molekylär cellbiologi;

    Sammanfattning : Pseudomonas aeruginosa is an opportunistic pathogen that can cause life-threatening infections in immunocompromised patients. It uses a type III secretion dependent mechanism to translocate toxic effector proteins directly into the eukaryotic cell. LÄS MER

  4. 3. Host-Pathogen Interactions in Pseudomonas aeruginosa Invasive and Respiratory Tract Infection

    Författare :Magnus Paulsson; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseudomonas aeruginosa; vitronectin; Respiratory tract infections; Innate Immunity; outer membrane vesicles; outer membrane proteins; beta-lactamase; ciprofloxacin; combination treatment; bacteraemia; Complement escape;

    Sammanfattning : Pseudomonas aeruginosa is an opportunistic bacterium that causes debilitating infections when the immune defence is compromised. It possesses an arsenal of virulence traits to colonize most compartments of the body and is often highly resistant against commonly used antimicrobial drugs. LÄS MER

  5. 4. Carbapenem resistance in Pseudomonas aeruginosa

    Författare :Christian Giske; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Carbapenem (imipenem and meropenem) resistance in Pseudomonas aeruginosa is increasing, with global resistance rates approaching 20%. The most common resistance mechanisms are down-regulation of the porin OprD, and increased activity of multi-drug efflux pumps, primarily MexAB-OprM. LÄS MER

  7. 5. STRUCTURAL, FUNCTIONAL AND EVOLUTIONARY STUDIES OF ANTIMICROBIAL PEPTIDES

    Författare :Mukesh Pasupuleti; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amphipathicity and end-tagging protease susceptibility; anaphylatoxin C3a; P. aeruginosa; S. aureus; innate immunity; amphipathic molecules; Antimicrobial peptides; infectious disease; bacteriostatic; microbicidal and cytolytic properties;

    Sammanfattning : Antimicrobial peptides represent a heterogeneous group that displays multiple modes of action such as bacteriostatic, microbicidal and cytolytic properties that are sequence and concentration dependent. Life threatening infectious disease is now a worldwide crisis and treating them effectively is becoming difficult day by day, due to the emergence of antibiotic resistant strains at alarming rates. LÄS MER