Sökning: "Novel Method"
Visar resultat 1 - 5 av 2351 avhandlingar innehållade orden Novel Method.
1. Targeted analysis of bioactive steroids and oxycholesterols : Method development and application
Sammanfattning : Peripheral steroids and oxycholesterols are important lipid compounds controlling various functions in the human body. Steroid analysis of biological samples is routinely employed in the clinical environment as an essential source of information on endocrine and metabolic disorders. LÄS MER
2. A Novel Immersed-Boundary Method for Multiple Moving and Interacting Bodies
Sammanfattning : This thesis describes the development, implementation and validation of an implicit, second order accurate, finite-volume and instationary immersed-boundary method for simulating the detailed flow around multiple arbitrary moving and interacting bodies. The potential for flows including moving bodies or boundaries, such as multiphase flows still has to be fully realized. LÄS MER
3. Drug Repositioning for Cancer Treatment : Novel Candidate Identification Strategies
Sammanfattning : Regardless of the enormous investments in cancer research and drug development, the proportion of approved drugs in oncology is low compared to other indications, and new avenues are needed. One attractive approach in this regard is drug repositioning where new uses outside the scope of the original medical indications for existing drugs are identified. LÄS MER
4. Transmission Electron Microscopy of Graphene and Hydrated Biomaterial Nanostructures : Novel Techniques and Analysis
Sammanfattning : Transmission Electron Microscopy (TEM) on light element materials and soft matters is problematic due to electron irradiation damage and low contrast. In this doctoral thesis techniques were developed to address some of those issues and successfully characterize these materials at high resolution. LÄS MER
5. Ribosomal translocation in real time : Method development to Applications
Sammanfattning : Translational elongation is the process in which the ribosome adds one amino acid at a time to the nascent peptide chain. As the ribosome elongates the peptide chain by 14 - 20 amino acids per second and performs hundreds of such cycles per protein, ‘elongation’ is one of the most crucial steps in translation. LÄS MER