Sökning: "GTP hydrolysis"
Visar resultat 1 - 5 av 21 avhandlingar innehållade orden GTP hydrolysis.
1. Characterizing Elongation of Protein Synthesis and Fusidic Acid Resistance in Bacteria
Sammanfattning : Protein synthesis is a highly complex process executed by the ribosome in coordination with mRNA, tRNAs and translational protein factors. Several antibiotics are known to inhibit bacterial protein synthesis by either targeting the ribosome or the proteins factors involved in translation. LÄS MER
2. Ribosomal translocation in real time : Method development to Applications
Sammanfattning : Translational elongation is the process in which the ribosome adds one amino acid at a time to the nascent peptide chain. As the ribosome elongates the peptide chain by 14 - 20 amino acids per second and performs hundreds of such cycles per protein, ‘elongation’ is one of the most crucial steps in translation. LÄS MER
3. Mechanisms for control of nucleoside triphosphate hydrolysis. Effects of DNA and RNA co-factors
Sammanfattning : In energetically unfavourable biological processes "protein machines" utilize chemical energy from the hydrolysis of high-energy phosphate bonds. Thus, the hydrolysis of a nucleoside triphosphate (NTP) to nucleoside diphosphate (NDP) with the release of free orthophosphate results in a liberation of energy. LÄS MER
4. The Protein Traffic on the Ribosome : The Mechanism and Regulation of Protein Synthesis in Prokaryotes
Sammanfattning : The aim of this work was to understand the molecular mechanism of translation and the mechanism of translation termination, in particular. Cleavage of peptidyl-tRNA and peptide release terminates translation of mRNA on the ribosome. In prokaryotes, three release factors (RFs) are involved in this process. LÄS MER
5. Elongation factor 2: A key component of the translation machinery in eukaryotes : Properties of yeast elongation factor 2 studied in vivo
Sammanfattning : Synthesis of proteins is performed by the ribosome, a large ribonucleoprotein complex. Apart from the ribosome, numerous protein factors participate in this process. Elongation factor 2 (eEF2) is one of these factors. eEF2 is an essential protein with a mol. LÄS MER