Sökning: "magnetic beads DNA coils"

Hittade 4 avhandlingar innehållade orden magnetic beads DNA coils.

  1. 1. Detection of Biomolecules Using Volume-Amplified Magnetic Nanobeads

    Författare :Teresa Zardán Gómez de la Torre; Maria Strømme; Peter Svedlindh; Mikkel Fougt Hansen; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic biosensor; magnetic nanobeads; Brownian relaxation; padlock probe; rolling circle amplification; DNA detection; protein detection; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

    Sammanfattning : This thesis describes a new approach to biomolecular analysis, called the volume-amplified magnetic nanobead detection assay (VAM-DNA). It is a sensitive, specific magnetic bioassay that offers a potential platform for the development of low-cost, easy-to-use diagnostic devices. LÄS MER

  3. 2. Biomolecular Recognition Based on Field Induced Magnetic Bead Dynamics

    Författare :Rebecca Stjernberg Bejhed; Peter Svedlindh; Klas Gunnarsson; Maria Strömme; Teresa Zardán Gómez de la Torre; Christer Johansson; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Magnetic biosensor; magnetic nanoparticle; DNA detection; Teknisk fysik; Engineering Science;

    Sammanfattning : In this thesis, three different read-out techniques for biomolecular recognition have been studied. All three techniques rely on the change in dynamic behaviour of probe functionalised magnetic beads after binding to a biomolecular target complementary to the probe. LÄS MER

  4. 3. Molecular Diagnostics Using Volume-Amplified Magnetic Nanobeads : Towards the Development of a Novel Biosensor System

    Författare :Mattias Strömberg; Maria Strømme; Peter Svedlindh; Mikkel Fougt Hansen; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic Biosensors; Ferrofluid; Biofunctionalisation; Ferrofluidic Aging; Interbead Interactions; Magnetic Nanobeads; Complex Magnetisation; Brownian Relaxation; Padlock Probes; Rolling Circle Amplification; Engineering physics; Teknisk fysik;

    Sammanfattning : Micro- or nanometer sized magnetic particles (beads) currently have a vast range of life science applications in, for example, bioseparation techniques, cancer therapy, development of contrast agents and biosensing techniques. In the latter field, magnetic beads offer several unique advantages, including minimal background signals, physical and chemical stability and low manufacturing costs. LÄS MER

  5. 4. Transmission Electron Microscopy of Graphene and Hydrated Biomaterial Nanostructures : Novel Techniques and Analysis

    Författare :Sultan Akhtar; Klaus Leifer; Hilborn Jöns; Stefano Rubino; Marco Cantoni; Uppsala universitet; []
    Nyckelord :Graphene flakes; magnetic beads DNA coils; hydrated biomaterials; transmission electron microscopy; focused ion beam scanning electron microscopy; bright-field dark-field imaging; high resolution imaging; electron diffraction and cryogenic temperatures; Materialvetenskap; Materials Science;

    Sammanfattning : Transmission Electron Microscopy (TEM) on light element materials and soft matters is problematic due to electron irradiation damage and low contrast. In this doctoral thesis techniques were developed to address some of those issues and successfully characterize these materials at high resolution. LÄS MER