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Visar resultat 1 - 5 av 12 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Avian MHC : Characterization and expression patterns of classical and non-classical MHC-I genes

    Författare :Anna Drews; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MCH class I; Classical genes; Non-classical genes; Expression; Passerine birds;

    Sammanfattning : The function of the vertebrate immune system is to enable recognition and elimination of microorganisms that can cause harm (pathogens). A key component in adaptive immunity is the major histocompatibility complex (MHC) that codes for molecules with antigen presentation function. LÄS MER

  3. 2. Non-classical regulation of gene transcription : a study of the human PDGF-B, H19 and IGF2 genes

    Författare :Gail I. R. Adam; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  4. 3. The MHC genes: variation and impact on life-history traits in house sparrwos

    Författare :Maria Karlsson; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MHC-I; house sparrow; 454-amplicon sequencing; cDNA; functional clustering; trans-species evolution; nestling survival; mate-choice;

    Sammanfattning : In birds the major histocompatibility complex (MHC) organization differs both among and within orders. Galliformes often have simple arrangements with few transcribed MHC genes whilst many songbirds (Passeriformes) have a complex arrangement with many MHC genes and also presence of pseudo-genes. LÄS MER

  5. 4. Genomic imprinting and DNA epigenetic modification in human liver and carcinogenesis : regulation of the IGF2 and H19 genes

    Författare :Xuri Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Genomic imprinting, which is an non-classical genetic event discovered approximately a decade ago, has been shown to be involved in the mammalian development and several kinds of human diseases. Epigenetic modifications, such as DNA methylation, are believed to be markers functioning as the imprinting signals. LÄS MER

  7. 5. Genetic changes in lymphoid leukemia

    Författare :Marianne Hammarsund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CLL; HCL; genetic aberrations; 13q14; chromosome 5; antisense; bicistronic;

    Sammanfattning : It is today generally accepted that the vast majority of malignant tumors arise as a result of genetic changes in critical genes involved in the tightly regulated control of cell growth and cell death. Despite the remarkable progress in the identification of such genes during the past two decades, many cancer genes probably remain to be identified. LÄS MER