Sökning: "Classical genes"
Visar resultat 1 - 5 av 147 avhandlingar innehållade orden Classical genes.
1. Avian MHC : Characterization and expression patterns of classical and non-classical MHC-I genes
Sammanfattning : The function of the vertebrate immune system is to enable recognition and elimination of microorganisms that can cause harm (pathogens). A key component in adaptive immunity is the major histocompatibility complex (MHC) that codes for molecules with antigen presentation function. LÄS MER
2. Non-classical regulation of gene transcription : a study of the human PDGF-B, H19 and IGF2 genes
Sammanfattning : .... LÄS MER
3. Studies of immunoglobulin light chains in rainbow trout (Oncorhynchus mykiss): new insight into the evolution of immunoglobulin genes
Sammanfattning : In this thesis, the structure and the expression of immunoglobulin (Ig) light chain genes were studied in rainbow trout and including an evolutionary perspective. A novel Ig light chain locus (IgL2) was identified and characterized. LÄS MER
4. Structure, evolution and expression of glandular kallikrein genes
Sammanfattning : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. LÄS MER
5. Inflammation and Intestinal Homeostasis-Associated Genes in Colorectal Cancer
Sammanfattning : Colorectal cancer (CRC) is a global ‘killer’ and every year more than 1.2 million new individuals are affected and approximately 600 000 succumb to the disorder. Several mechanisms such as inactivation of tumor suppressor genes, activation of oncogenes and dysregulation of cell fate determinating pathways e.g. LÄS MER