Sökning: "NADPH diaphorase"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden NADPH diaphorase.

  1. 6. Dopachrome and aminochrome, the oxidized metabolites of dopa and dopamine : studies on the molecular mechanisms underlying their reduction and conjugation with glutathione

    Författare :Sofia Baez; Francisco Solano Munoz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : Dopamine, like other catecholamines can be oxidized to the corresponding ortho-quinone, which undergoes cyclization of its amino chain to cyclized dopamine ortho-quinone (aminochrome). Both o-quinones are toxic metabolites that may contribute to neurotoxic effects of these catecholamines. LÄS MER

  3. 7. Cellular toxicity of quinones : Redox- and addition chemistry

    Författare :Karin Öllinger; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Quinoid compounds are widely occurring in nature. They have cytotoxic properties and they are also used as antineoplastic agents. The cytotoxic properties can be explained by the ability of quinones to generate active oxygen species by redox cycling, by addition to cellular nucleophiles, and by inhibition of DNA transcription. LÄS MER

  4. 8. On the role of nitric oxide in uterine secretion

    Författare :Birgitta Mörlin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Autonomic nerves; endometrial and cervical secretion; nitric oxide; guineapig.;

    Sammanfattning : Background: Uterine secretion is important in many different aspects of reproduction e.g. sperm transport and survival, fertilization, nourishment of the ovum and implantation. A cholinergic autonomic nervous secretory innervation has been established and modulation of the secretion by prostaglandins and NSAID drugs has been postulated. LÄS MER