Sökning: "Metyrapone"

Visar resultat 6 - 10 av 11 avhandlingar innehållade ordet Metyrapone.

  1. 6. The importance of monocyte and granulocyte activation in rheumatoid arthritis and primary Sjögren's syndrome

    Författare :Ingunn Torsteinsdóttir; Uppsala universitet; []
    Nyckelord :Medical sciences; Rheumatoid arthritis; primary Sjögren s syndrome; peripheral blood; monocyte; macrophage; neutrophil; eosinophil; adhesion; phagocytosis; respiratory burst; CRP; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Macrophages and neutrophils infiltrate the synovium and synovial fluid in rheumatoid arthritis (RA). These cells are considered to contribute to the destructive process in RA.The expression of adhesion and phagocytosis receptors on the surface of peripheral granulocytes and monocytes was increased in patients with RA. LÄS MER

  3. 7. Interaction of Xenobiotics with the Glucocorticoid Hormone System in vitro

    Författare :Maria Johansson; Helen Håkansson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; DDT; PCB; tolylfluanid; adrenal; CYP11B1; glucocorticoid receptor; endocrine disrupter; Biologi; Biology; Biologi; Ecotoxicology; ekotoxikologi;

    Sammanfattning : Persistent environmental pollutants were examined for their interaction with the glucocorticoid hormone system. The focus was placed on interference with the glucocorticoid synthesis and the glucocorticoid-signalling pathway in various in vitro test systems. LÄS MER

  4. 8. Microsomal epoxide hydrolase : characterization, induction, and in vitro modulation, of the catalytic activity

    Författare :Janeric Seidegård; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Microsomal epoxide hydrolase has been characterized, mainly in the fiver and lung of the rat.A reported radiometric assay using 3H-styrene 7,8-oxide as substrate has been modified by purifying the substrate before use, decreasing the incubation volume, and prolonging the incubation time. LÄS MER

  5. 9. Studies on 7a-hydroxycholesterol in extrahepatic tissues and cells

    Författare :Jie Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In human liver, primary bile acids are synthesized from cholesterol via the well-established neutral and also via the recently described acidic pathways. The latter includes 27-hydroxycholesterol 7alpha-hydroxylase. LÄS MER

  7. 10. Endogenous and exogenous glucocorticoid effects in a model of allergic airway inflammation

    Författare :Susanna Kumlien Georén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Airway; allergy; asthma; eosinophil; glucocorticoids; hypothalamus-pituitary-adrenal HPA axis; inflammation; nerve growth factor NGF ; neuroimmunology; psychoneuroimmunology; restraint; stress;

    Sammanfattning : Allergic asthma and rhinitis are inflammatory diseases of the airways. Allergic asthma is characterized by eosinophilic inflammation, reversible bronchoconstriction and airway hyperresponsiveness, whereas patients with rhinitis suffer from nasal inflammation, leading to rhinorrhea and nasal congestion. LÄS MER