Sökning: "MHC class-I related chain A"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden MHC class-I related chain A.

  1. 1. MHC class I - Peptide binding and complex stability

    Författare :Elna Follin; Antigen presentation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The major histocompatibility class I (MHC-I) genes are highly polymorphic and the proteins that they encode play a crucial role in both the innate and the adaptive immune response. A MHC-I molecule consists of three parts, one polymorphic heavy chain, one invariant light chain, β2-microglobulin and a peptide of usually between 8-11 amino acids in length. LÄS MER

  3. 2. Mechanisms of endothelial cell dysfunction in Wegener's granulomatosis

    Författare :Carolina Holmén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Wegener´s granulomatosis; vasculitis; anti-endothelial cell antibody; circulating endothelial cell; vascular adhesion protein 1; MHC class-I related chain A;

    Sammanfattning : Vasculitides are a heterogeneous group of disorders that share a common feature of blood vessel inflammation. A major cell type of the blood vessel affected is the endothelial cell (EC). LÄS MER

  4. 3. HLA predisposition to human papillomavirus induced cervical neoplasia : population based studies from the Västerbotten county in northern Sweden

    Författare :Mehran Ghaderi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Infection with human papillomaviruses (HPV) types 16 and 18 is the major cause of cervical neoplasia. Although a high proportion of cervical cancers (CXCA) harbor HPV genomes, only a small number of women infected with high-risk papillomaviruses develop cervical tumors, suggesting that other environmental and/or genetic factors contribute to cervical carcinogenesis. LÄS MER

  5. 4. Immunological consequences of Epstein-Barr virus replication

    Författare :Andre Ortlieb Guerreiro Cacais; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus involved in the pathogenesis of a wide spectrum of malignant and non-malignant diseases. In healthy EBV carriers, the virus is believed to infect two major cellular targets - B lymphocytes and epithelial cells. LÄS MER

  7. 5. Human papillomavirus in sinonasal inverted papilloma, recurrent respiratory papilloma and non-malignant tonsils

    Författare :Anna M. Holm; Katarina Olofsson; Karin Nylander; Göran Laurell; Stina Syrjänen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; recurrent respiratory papillomatosis; sinonasal inverted papilloma; non-malignant tonsillar disease; Epstein-Barr virus; immune system; p16; Hyaluronan; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Background: Human papillomavirus (HPV) is known to cause recurrent respiratory papilloma (RRP) and certain types of oropharyngeal cancer. HPV has also been associated with sinonasal inverted papilloma (SIP). LÄS MER