Sökning: "Lovisa Bylund"

Hittade 1 avhandling innehållade orden Lovisa Bylund.

1. 1. Functional studies of the multiple endocrine neoplasia type 1 gene

   Författare :Lovisa Bylund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEN1; menin; tumor suppressor gene; cancer; RNAi; promoter; expression; cytogenetic; microarray;

   Sammanfattning : The multiple endocrine neoplasia type 1 (MEN1, OMIM 131 100) syndrome is an autosomal dominant trait with a near 100% penetrance and with an estimated prevalence of 2-20/100 000. The syndrome is characterized by neoplasia affecting the parathyroid glands (90-97%), enteropancreatic endocrine tissues (30-80%) and the anterior pituitary gland (15-50%) but tumors arc also found in other, both endocrine and non endocrine tissues. LÄS MER