Avancerad sökning

Hittade 1 avhandling som matchar ovanstående sökkriterier.

1. 1. Roles of protein kinase C in cell death and breast cancer

   Författare :Louise Cornmark; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; protein kinase C; apoptosis; cell death; Smac; Smac mimetics; IAP; stanniocalcin-1;

   Sammanfattning : Aberrant protein kinase C (PKC) activity and expression is implicated in different malignancies. To study the role of different PKC isoforms in breast cancer the expression of PCKα, δ and ε was evaluated in breast cancer tumors. In addition the effect of siRNA-mediated knockdown of the isoforms was studied in a global gene expression analysis. LÄS MER