Sökning: "stanniocalcin-1"

Hittade 2 avhandlingar innehållade ordet stanniocalcin-1.

  1. 1. Roles of protein kinase C in cell death and breast cancer

    Författare :Louise Cornmark; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; protein kinase C; apoptosis; cell death; Smac; Smac mimetics; IAP; stanniocalcin-1;

    Sammanfattning : Aberrant protein kinase C (PKC) activity and expression is implicated in different malignancies. To study the role of different PKC isoforms in breast cancer the expression of PCKα, δ and ε was evaluated in breast cancer tumors. In addition the effect of siRNA-mediated knockdown of the isoforms was studied in a global gene expression analysis. LÄS MER

  2. 2. Exploring functional subsets of cancer-associated fibroblasts

    Författare :Michael Bartoschek; Avdelningen för translationell cancerforskning; []
    Nyckelord :;

    Sammanfattning : The tumor microenvironment consists of several interacting cell types. Cancer research focssed mainly on the malignant cell in the past. The importance of the tumor microenvironment is increasingly appreciated, as endothelial cells and immune cells were identified as targets for anti-tumor therapy. LÄS MER