Sökning: "Long term potentiation"

Visar resultat 11 - 15 av 33 avhandlingar innehållade orden Long term potentiation.

  1. 11. Plasticity and variation of synaptic responses in hippocampus. Role of AMPA and NMDA receptors

    Författare :Yin-Ping Niu; Göteborgs universitet; []
    Nyckelord :learning and memory; synaptic plasticity; hippocampus; synapse; AMPA receptor; NMDA receptor; LTP; LTD; CV; TFS;

    Sammanfattning : It is generally believed that synaptic plasticity in the central nervous system may underlie learning and memory as well as neuronal development. The most wellstudied examples of such synaptic plasticity are long-term potentiation (LTP) andlong-term depression (LTD). LÄS MER

  3. 12. Re-evaluation of the hypothesis that LTP has two temporal phases and that the late phase is protein synthesis-dependent

    Författare :Abdul-Karim Abbas; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine;

    Sammanfattning : Long-term potentiation (LTP) is an activity-dependent increase in synaptic efficacy that is most studied in the hippocampus and that is considered a cellular substrate for learning and memory. Accepting the belief that the durability (persistence in time) of LTP is analogical to long-standing store of hippocampus-dependent memories warrants the necessity for understanding the mechanisms underlying LTP stabilization. LÄS MER

  4. 13. Synaptic plasticity in local networks of neocortical layer 2/3

    Författare :Misha Zilberter; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neocortical microcircuit; layer 2 3; pyramidal cell; spike timing- dependent plasticity; LTP; LTD; FSN interneuron; retrograde signalling; SAT2;

    Sammanfattning : The neocortex is a hierarchal organ in which information processing takes on place on many levels, from subcellular signalling all the way to neural networks. Neocortical local neuronal networks (microcircuits), composed of interconnected neurons, form elementary information processing units within the cortex. LÄS MER

  5. 14. On the Mechanisms Behind Hippocampal Theta Oscillations : The role of OLMα2 interneurons

    Författare :Sanja Mikulovic; Richardson Leao; Klas Kullander; Stefan Remy; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hippocampus; interneuron; optogenetics; theta oscillations; anxiety;

    Sammanfattning : Theta activity is one of the most prominent rhythms in the brain and appears to be conserved among mammals.  These 4-12 Hz oscillations have been predominantly studied in the dorsal hippocampus where they are correlated with a broad range of voluntary and exploratory behaviors. LÄS MER

  7. 15. Non-linear synaptic integration on dendrites of striatal medium-spiny neuron : a computational study

    Författare :Kai Du; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Striatum is the main input nucleus of basal ganglia. Medium-spiny neurons (MSNs), the principal neurons of the striatum, receive convergent excitatory inputs from cortex and thalamus, thus “gate” the information flow to the basal ganglia. LÄS MER