Sökning: "Laminins"

Visar resultat 16 - 20 av 28 avhandlingar innehållade ordet Laminins.

1. 16. Interaction of human blood platelets, lymphocytes and monocytes with vascular laminin isoforms

   Författare :Gezahegn Gorfu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Vascular laminin isoforms; extracellular matrix; integrins; cell adhesion; cell migration; high endothelial venules; lymphocytes; monocytes; platelets; leukocyte extravasation;

   Sammanfattning : Inflammatory and immune responses play a fundamental role in both health and disease, and leukocytes are important actors in these processes. Migration of the leukocytes to sites of injury or inflammation is a crucial component of innate and adaptive immunity. It is currently accepted that leukocyte extravasation is a multistep process. LÄS MER

3. 17. Primary structure, expression and function of laminin [alpha]4

   Författare :Jarkko Kortesmaa; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Basement membranes (BMs) are thin extracellular sheet-like structures that compartmentalize tissues. They are found beneath epithelia and endothelia, and surrounding individual cells, such as muscle fibers, neurons and adipocytes. Laminins, type IV collagens, perlecan and nidogens are some of the main components of mature basement membranes. LÄS MER

4. 18. Laminin-1 and receptors : Laminin α1 chain in important for epithelial development

   Författare :Mats Falk; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; basement membrane; gene targeting; laminin α1; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : Laminins are heterotrimeric glycoproteins that are major components of all basement membranes. Integrins from the β1 -famjly and the dystroglycan complex have been shown to be important receptors attaching epithelial cells to the underlying basement membrane. LÄS MER

5. 19. Cellular Interactions with Extracellular Matrix During Development and in Muscle Disease

   Författare :Carl-Fredrik Tiger; Anders Aspberg; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; integrin; laminin; collagen; muscle; tendon; skeleton; mouse; human; development; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : The formation and maintenance of tissues in multicellular animals are crucially dependent on cellular interactions with the extracellular matrix (ECM). Two different studies on such interactions are presented herein. LÄS MER

7. 20. Functional studies of integrin subunit 1 and its cytoplasmic domain

   Författare :Krister Wennerberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; integrin; integrin subunit β1; integrin signaling; extracellular matrix; fibronectin polymerisation; focal adhesions; focaladhesion kinase; metastasis; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Sammanfattning : Integrin subunit β1 can form functional heterodimeric receptors together with at least 11different a subunits. These integrins are the main cellular receptors for extracellular matrixproteins such as collagens, fibronectin, laminins, and others, and they are necessary fornormal embryonal development. LÄS MER