Sökning: "Laia"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Laia.

  1. 1. Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

    Författare :Laia Gorchs; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : About 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC) and its deadly hallmarks, including a prominent fibrotic stroma, low mutational burden, lack of early diagnosis and rapid metastasis, contribute to trial failures and to the poor five-year overall survival rate of only 9%. Carcinoma associated fibroblasts (CAFs) are the most abundant cell type in the stroma of PDAC and their interactions with tumor cells leading to tumor progression have been extensively studied. LÄS MER

  3. 2. Modulating chromatin by transcription and nucleosome turnover : a genome-wide study in fission yeast

    Författare :Laia Sadeghi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Eukaryotic DNA is wrapped around histone proteins to form a nucleosome, the basic structural unit of chromatin. Multiple levels of chromatin organization are required to compact DNA into chromosomes, to ensure an accurate cell division. LÄS MER

  4. 3. Role of tartrate-resistant acid phosphatase in bone remodeling

    Författare :Laia Mira-Pascual; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tartrate-resistant acid phosphatase is a metalloenzyme that exists as two isoforms: the monomeric TRAP 5a and the proteolytically cleaved TRAP 5b, responsible for phosphatase activity, which is highly expressed in osteoclasts (OCs). TRAP 5b has been used as a serum marker of bone resorption, as it correlates with the absolute number of OCs and with resorption markers such as CTX-I. LÄS MER

  5. 4. Distant supernovae and galaxies in the Stockholm VIMOS Supernova Survey

    Författare :Laia Mencia Trinchant; Göran Östlin; Duilia F de Mello; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; imaging surveys; photometric redshfits; Lyman Break galaxies; supernova typing; supernova rates; supernova host galaxies; Astronomy; Astronomi; Astronomy; astronomi;

    Sammanfattning : Multi colour imaging surveys help astronomers to find galaxies and clusters,and to gain insights on their physical properties and evolution. In this thesis, I present the Stockholm VIMOS Supernova Survey (SVISS), where the ELAIS-S field was observed with VIMOS UBVRI broad-band optical bands over a period of 5 years. LÄS MER

  7. 5. Designing for Intercorporeality : An Interaction Design Approach to Technology-Supported Movement Learning

    Författare :Laia Turmo Vidal; Annika Waern; Dag Svanæs; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Interaction Design; Movement Learning; Movement Teaching; Biofeedback; Wearables; Constructive Design Research; Research through Design; Practice Design; Soma Design; Technology Probes; Strong Concept; Movement Aesthetics; Människa-dator interaktion; Human-Computer Interaction;

    Sammanfattning : Technology-supported movement learning has emerged as an area with ample possibilities within Human Computer Interaction and Interaction Design, as interactive technology can help people to develop and improve sensorimotor competencies. To date, design research has largely focused on technology development and on supporting individual learning experiences. LÄS MER