Sökning: "Th17"
Visar resultat 1 - 5 av 63 avhandlingar innehållade ordet Th17.
1. Genital tract CD4+ T cells for vaccination and protection against Chlamydia trachomatis
Sammanfattning : Vaccination strategies for protection against sexually transmitted diseases (STDs) are lacking due to an incomplete understanding of genital tract T cell responses. This thesis dissects the generation of T helper subsets, including the recently discovered Th17 subset, during genital tract infection with a common sexually transmitted pathogen, Chlamydia trachomatis, and addresses vaccine requirements for the generation of genital tract CD4+ T cell immunity. LÄS MER
2. Humoral and cellular immune response to Helicobacter pylori in Bangladeshi children and adults that may be related to protection
Sammanfattning : Helicobacter pylori (Hp) colonizes the human gastric and duodenal mucosa and the infection may cause peptic ulcers and gastric adenocarcinoma. Half of the world’s population is infected with Hp with the highest prevalence in developing countries. LÄS MER
3. Lung-resident, M2e-specific CD4 T cells critically protect during influenza infection
Sammanfattning : Memory CD4+ T cells are a critical component of the adaptive immune response to fight infection. However, current vaccines against influenza only focus on the other arm of adaptive immunity—triggering B cells to produce antibodies. LÄS MER
4. Mechanistic studies of the adjuvant effects of CTA1-DD and the native cholera toxin: Impact of cell targeting and tissue localization
Sammanfattning : Vaccines are the most effective means of preventing infectious diseases and improving global health. However, few vaccines have successfully been developed for protection at mucosal surfaces where most pathogens gain access. LÄS MER
5. Regulation of gut IgA induction by helper T cells
Sammanfattning : The gut is the largest lymphoid organ in the body. Due to intense and constant exposure to the outside world, it also functions as the most important portal of entry for many pathogens. LÄS MER