Sökning: "IGFBP-1 IGF-I"

Visar resultat 6 - 10 av 28 avhandlingar innehållade orden IGFBP-1 IGF-I.

  1. 6. The IGF-IGFBP system in aerobic exercise : with focus on skeletal muscle

    Författare :Ulrika Berg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IGF-I; IGFBP-1; microdialysis; exercise; IL-6; calpain;

    Sammanfattning : Activity induced skeletal muscle adaptation has been suggested to be mediated largely by intrinsic factors, such as insulin-like growth factor (IGF)-I. IGF-I stimulates muscle glucose and amino acid uptake and promotes anabolism. LÄS MER

  3. 7. Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control

    Författare :Ingmar Zachrisson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 1 diabetes; Puberty; Adolescence; Metabolic Control; IGF-I; IGFBP-1; IGFBP-3; Proteases; Leptin;

    Sammanfattning : It is well known that, in children with type 1 diabetes, metabolic control often deteriorates during puberty. Better understanding of the mechanisms that cause deterioration of blood glucose control can lead to improved therapeutic approaches. LÄS MER

  4. 8. Novel insulin-like growth factor-binding protein proteases : detection and characterization

    Författare :Jing Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IGFs; IGFBP-1. IGFBP-3; azurocidin HBP CAP37; IGFBP protease; gender;

    Sammanfattning : Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins (IGFBP-1 to -6) control the availability of IGFs (IGF-I and IGF-II) to their receptors. LÄS MER

  5. 9. Growth factors and vasoactive substances in intrauterine growth restriction and preeclampsia

    Författare :Eva Östlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cordocentesis; IUGR; preeclampsia; prediction; IGF-I; IGFBP- 1; TGF-beta 1; blood gases; hypoxia; vasoconstriction; endothelin; erythropoietin; fibronectin; placenta.;

    Sammanfattning : Fetal growth restriction (FGR) is, next to prematurity, the second leading cause of perinatal morbidity and mortality. To reduce perinatal morbidity and mortality it is important to identify such fetuses in utero in order to monitor their development, and to determine the most optimal time for delivery. LÄS MER

  7. 10. Insulin treatment of elderly type 2 diabetic patients

    Författare :Jonas Tovi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 diabetes; elderly; insulin treatment; costs; ambulatory blood pressure; monitoring; well-being; symptoms; polyneuropathy; IGFBP-1 IGF-I; retinopathy;

    Sammanfattning : In this study, the effect of improved metabolic control through insulin treatment was investigated in elderly patients with type 2 diabetes with secondary failure of oral treatment. Forty, consecutive, elderly patients (mean age 75.3 (5.9) (mean and SD), range 67-86 years) were studied. LÄS MER