Sökning: "Puberty"
Visar resultat 1 - 5 av 88 avhandlingar innehållade ordet Puberty.
1. Childhood Body Mass Index and Pubertal Timing - Changes over time and associations with adult cardiovascular mortality
Sammanfattning : Puberty in boys has long been an under-investigated area of research mainly due to the lack of an easily available pubertal marker, corresponding to menarche for girls. Using a unique, large, population-based cohort, this thesis targets some of the knowledge gaps regarding puberty and BMI change during puberty in boys. LÄS MER
2. Human growth patterns - with focus on pubertal growth and secular changes
Sammanfattning : Introduction: Human growth is a dynamic process, an indicator of health and disease. Previous used growth models have been limited in describing the pubertal growth spurt. Aim: The overall aim of this thesis is to increase knowledge regarding human growth. LÄS MER
3. Testosterone and 17beta-oestradiol secretions in children and adolescents. Assay development, levels for comparison and clinical applications
Sammanfattning : Accurate measurements of 17beta-oestradiol and testosterone are important in clinical settings of pubertal disorders and hormone replacement therapy among children. Most assays for measurement of these steroids are optimised for fertility investigations in adults and are not sensitive enough for quantification in children. LÄS MER
4. On the developmental significance of female pubertal timing
Sammanfattning : Puberty is the process of becoming sexually mature and it has fundamental somatic and psychosocial implications. The focus of this dissertation was the short and long term developmental significance, concerning both soma et psyche, of female pubertal timing. Four studies were designed to accomplish these aims. LÄS MER
5. Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment
Sammanfattning : The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. LÄS MER