Sökning: "azurocidin HBP CAP37"
Hittade 4 avhandlingar innehållade orden azurocidin HBP CAP37.
Sammanfattning : Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins (IGFBP-1 to -6) control the availability of IGFs (IGF-I and IGF-II) to their receptors. LÄS MER
Sammanfattning : Infectious diseases remain a major health problem, where sepsis and other severe bacterial infections are common causes of morbidity and mortality, and are associated with high costs for the community. The importance of early and appropriate treatment of sepsis and severe bacterial infections has been underlined by many and since sepsis is more prevalent and has a higher mortality rate than for instance acute myocardial infarction, there is a need for improvement. LÄS MER
Sammanfattning : This thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. LÄS MER
Sammanfattning : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. LÄS MER