Sökning: "Host defenses"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Host defenses.

  1. 1. Nitrite ion : its role in vasoregulation and host defenses

    Författare :Håkan Björne; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nitrate; nitrite; nitric oxide; gastro protection; ventilator-associated pneumonia; bactericidal; vasodilation;

    Sammanfattning : Nitrite and nitrate are distributed throughout the human body, with especially high levels being present in saliva. Until recently, these anions were considered merely to be inert end-products of the oxidation of endogenous nitric oxide (NO). LÄS MER

  3. 2. The functional role of the MUC17-based glycocalyx

    Författare :Sofia Jäverfelt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intestine; Glycocalyx; Membrane mucin; Host defenses;

    Sammanfattning : Our gastrointestinal tract harbors trillions of bacteria that are chemically and spatially separated from the intestinal epithelium. Maintaining an intact mucosal barrier is essential as increased bacterial contact is associated with inflammatory bowel diseases such as Crohn´s disease. LÄS MER

  4. 3. On airway host defence during allergic inflammation

    Författare :Anele Gela; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :Asthma; COPD; Antimicrobial peptide; chemokines; immunology;

    Sammanfattning : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. LÄS MER

  5. 4. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Författare :Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. LÄS MER

  7. 5. Interaction Between Drosophila melanogaster mbn-2 Cells and Bacteria

    Författare :Karin Johansson; Kenneth Söderhäll; Lage Cerenius; Martin Bilej; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Drosophila; innate immunity; bacteria; host - pathogen interaction; Cellbiologi; Cell biology; Cellbiologi;

    Sammanfattning : Innate immunity relies on a repertoire of germline-encoded non-rearranging pattern recognition receptors that bind to invariant microbial surface molecules. This event initiates a number of signal transduction cascades that lead to humoral and cellular defense responses like synthesis of antimicrobial peptides, phagocytosis and coagulation – mechanisms that efficiently fight infectious microorganisms and have been evolutionary conserved to exist in parallel with the antibody-based adaptive immunity found in vertebrates. LÄS MER