Sökning: "High through put screening"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden High through put screening.
1. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels
Sammanfattning : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. LÄS MER
2. Aluminium alloy development for Additive Manufacturing
Sammanfattning : Powder Bed Fusion (PBF Additive Manufacturing AM have emerged as a promising manufacturing process possessing a powerful combination of characteristics. Most noticeable are the near-net-shape, short lead time and flexibility, both with regard in design freedom and in part-to-part variation. LÄS MER
3. Aspects in bioethics : Theory and practice in a preventive screening for type 1 diabetes
Sammanfattning : From a clinical perspective, as well as societal and global, the present rapid increase in the number of people diagnosed with diabetes is a cause of great concern. Simultaneously, our understanding of the aetiology and pathogenesis of type 1 diabetes (IDDM) remain limited. LÄS MER
4. Analysis of PDGF receptor internalization and signaling using proximity ligation assays
Sammanfattning : Cell signaling is mediated by signaling proteins that relay the signal in an intricate network of interactions before the signal is translated into a biological response. Short linear motifs (SLiMs) in intrinsically disordered regions of proteins serve as docking sites for protein interaction in all aspects of cell regulation including signal transduction. LÄS MER
5. Harnessing urinary extracellular vesicles microRNA by acoustic trapping as potential biomarkers for prostate cancer
Sammanfattning : Prostate cancer (PCa) is an interesting study case of clinical management of uncertainty. PCa is the most diagnosed but only the second-leading cause of non-cutaneous cancer-related mortalities among men in developed countries. To put simply, the life-time risk of PCa diagnosis and mortality is approximately 11% and 3% respectively; a ~3. LÄS MER